Results 81 to 90 of about 18,395,903 (215)
Advanced Science, EarlyView.An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin +18 more
wiley +1 more source
THE THEME OF THE DREAM IN THE LYRICS OF B.L. PASTERNAK: MYTHOPOETIC ASPECT
RUDN Journal of Studies in Literature and Journalism, 2016 The article considers the system of artistic hypnology in the lyrics of B. L. Pasternak. Detailed analysis from the point of view of mythopoetic be the group of poems in which the dream - plot motif.
G A Zakroyeva
doaj
Towards a Compositional Framework for Describing Human Phenotypes
Advanced Science, EarlyView.The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu +11 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals that age‐related LMNB1 deficiency in mesenchymal stem cells epigenetically upregulates SLC7A11, triggering actin disulfidptosis and mitochondrial dysfunction. This cascade impairs bone formation in senile osteoporosis. Furthermore, researchers identified the FDA‐approved drug naldemedine as a targeted SLC7A11 inhibitor to reverse ...
Wenhui Yu +12 more
wiley +1 more source
Personalized Sleep Parameters Estimation from Actigraphy: A Machine Learning Approach
Nature and Science of Sleep, 2019 Aria Khademi,1–3 Yasser EL-Manzalawy,1,4 Lindsay Master,5 Orfeu M Buxton,5–9 Vasant G Honavar1–3,6,10,11 1College of Information Sciences and Technology, The Pennsylvania State University, University Park, PA, USA; 2Artificial ...
Khademi A +4 more
doaj
Behavioral SciencesWorking at home, rather than in the workplace, has been suggested to affect office-based workers’ health and wellbeing. This exploratory, cross-sectional study sought to identify discrete psychological responses to home-working practices and investigate ...
Samuel Keightley +3 more
doaj +1 more source
Measuring a sleep/stress switch point [PDF]
The Spielman 3P and Cano-Saper models of insomnia focus on the role of stress in the development of insomnia. To date, the impact of both naturalistic stressors and experimental stressors upon sleep have been inconsistent, due to limitations including ...
Elder, Greg
core
, 2004 Study Objectives: To evaluate the influence of early life environments on basal and cold stress-induced sleep patterns in rats.Design: The design was a 3 (Groups [control, early handling, maternal separation]) x 2 (Situations [basal, poststress]) x 11 ...
Sergio Tufik +5 more
core +1 more source
Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics
Advanced Intelligent Discovery, EarlyView.Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong +5 more
wiley +1 more source
International Journal of Computational Intelligence SystemsTo maximize training programs and improve individual performance, the sports fitness profession is always looking for new and innovative solutions. Fuzzy decision support systems provide a strong basis for improving training regimen efficacy through ...
Peng An
doaj +1 more source