Results 101 to 110 of about 33,185 (230)

Challenges and pitfalls of experimental bariatric procedures in rats [PDF]

, 2012
Introduction: The impact of Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) on obesity and obesity-related diseases is unquestionable. Up to now, the technical descriptions of these techniques in animals/rats have not been very comprehensive.
Becker, Kristianna, Bruckner, Thomas, Büchler , Markus W., Clemens, Gabriella, Fischer, Lars, Gehrig, Tobias, Gutt, Carsten N., Kenngott, Hannes, Müller-Stich, Beat   +8 more
core   +1 more source

Gut Dysbiosis as a Shared Mechanism in Obesity and Hypertension: Exploring a Promising Therapeutic Avenue

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 3, May 2026.
This review synthesises current knowledge on gut microbiome involvement in obesity and hypertension, evaluates microbiome‐based therapeutic strategies, and identifies critical research gaps to guide future investigations aimed at mitigating the dual pandemics.
Andrej Belančić, Almir Fajkić, Yusuf Ziya Sener, Ana Jelaković, Lejla Alić, Elvira Meni Maria Gkrinia, Donatella Verbanac, Bojan Jelaković   +7 more
wiley   +1 more source

Long-term effect of sleeve gastrectomy vs Roux-en-Y gastric bypass in people living with severe obesity: a phase III multicentre randomised controlled trial (SleeveBypass)Research in context

The Lancet Regional Health. Europe
Summary: Background: Sleeve gastrectomy is the most performed metabolic surgical procedure worldwide. However, conflicting results offer no clear evidence about its long-term clinical comparability to Roux-en-Y gastric bypass.
L Ulas Biter, Judith WH. ‘t Hart, Bo J. Noordman, J Frans Smulders, Simon Nienhuijs, Martin Dunkelgrün, Johannes F. Zengerink, Erwin Birnie, Irene AM. Friskes, Guido HH. Mannaerts, Jan A. Apers   +10 more
doaj   +1 more source

Mechanisms underlying the weight loss effects of RYGB and SG: similar, yet different [PDF]

, 2018
The worldwide obesity epidemic continues unabated, adversely impacting upon global health and economies. People with severe obesity suffer the greatest adverse health consequences with reduced life expectancy.
Batterham, RL, Pucci, A
core   +1 more source

Pouch Surgery for Ulcerative Colitis: Navigating Complexity in the Modern Era

JCC Plus, Volume 1, Issue 3, May 2026.
ABSTRACT Restorative proctocolectomy with ileal pouch–anal anastomosis (IPAA) remains the preferred surgical treatment for patients with ulcerative colitis (UC) who require surgery but wish to avoid a permanent ileostomy. Since its introduction in 1978, IPAA has undergone continuous refinement in response to advances in both medical therapy and ...
Gabriele Bislenghi, Caroline Nordenvall, Anthony de Buck van Overstraeten, Peter Kienle, Alaa El‐Hussuna   +4 more
wiley   +1 more source

Is AMP‐activated protein kinase activation a central mechanism of cardio‐metabolic outcomes after metabolic and bariatric surgery?

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3480-3490, May 2026.
Abstract Metabolic and bariatric surgery (MBS) is the most effective treatment for severe obesity. It usually results in spectacular weight loss, associated with improvements of obesity‐associated comorbidities. The mechanisms underlying these benefits are not fully understood but could involve a postoperative activation of the enzyme 5′ AMP‐activated ...
Adrien Delcour, Nathalie Niederhoffer
wiley   +1 more source

Hypothalamic ghrelin receptors, weight loss, and glycemia in an experimentally induced obesity model treated by sleeve gastrectomy [PDF]

Acta Cirúrgica Brasileira
Purpose: Body weight, blood glucose, and hypothalamic ghrelin receptors were monitored in an animal model of obesity after being treated with sleeve gastrectomy.
Claudia Gissi da Rocha Ferreira, André Richter Ribeiro, Christiane Madrid Finck, Ana Paula Percicote, Jorge Eduardo Fouto Matias   +4 more
doaj   +1 more source

Type 2 diabetes subphenotypes are associated with differential outcomes after metabolic and bariatric surgery: An international multicentre retrospective cohort study

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3681-3691, May 2026.
Abstract Aims Type 2 diabetes (T2D) is characterized by its clinical heterogeneity. Newly described T2D subphenotypes, each with distinct metabolic and co‐morbidity risk profiles, may enable a more personalized care. This study examined whether these subphenotypes can predict outcomes in patients undergoing metabolic and bariatric surgery (MBS ...
Adisa Poljo, Jakob J. Reichl, Lars Kollmann, Piotr Kalinowski, Aleksandra Frankowska, Michał Grąt, Eleni A. Felinska, Ulrike Heger, Stefan Kopf, Donna Noeva, Christopher Tuffs, Matthias Hepprich, Eleonora Seelig, Ralph Peterli, Marko Kraljević, Jennifer M. Klasen, Beat P. Müller, Romano Schneider, Adrian T. Billeter   +18 more
wiley   +1 more source

Bariatric surgery in individuals with human immunodeficiency virus and type 2 diabetes: a case series

Journal of Medical Case Reports, 2019
Background The efficacy and safety of bariatric surgery have not been fully elucidated in patients affected with human immunodeficiency virus. Although adjustable gastric banding and sleeve gastrectomy are starting to be used in patients with human ...
Wei Yang, Anjali Zalin, Mark Nelson, Gianluca Bonanomi, James Smellie, Kevin Shotliff, Evangelos Efthimiou, Veronica Greener   +7 more
doaj   +1 more source

Acarbose or Canagliflozin vs. Placebo to Ameliorate Post‐Bariatric Hypoglycaemia: The Clinical Outcomes of the HypoBar I Randomised Clinical Trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4205-4215, May 2026.
ABSTRACT Aims Treatment options for post‐bariatric hypoglycaemia (PBH) are empirical. We aimed to investigate the efficacy and safety of acarbose and canagliflozin for the treatment of PBH. Materials and Methods We performed a randomised, double‐blinded, cross‐over, placebo‐controlled clinical trial where placebo, acarbose 50 mg thrice daily, and ...
Carolina B. Lobato, Clara Tornøe Winding, Kirstine N. Bojsen‐Møller, Bolette Hartmann, Christoffer Martinussen, Simon Veedfald, Jens J. Holst, Sten Madsbad, Nils Bruun Jørgensen, Carsten Dirksen   +9 more
wiley   +1 more source