Results 1 to 10 of about 922,264 (259)

Inhibition of rat locus coeruleus neurons by prostaglandin E2 EP3 receptors: pharmacological characterization ex vivo

open access: yesFrontiers in Pharmacology, 2023
Prostaglandin E2 (PGE2) is an inflammatory mediator synthesized by the brain constitutive cyclooxygenase enzyme. PGE2 binds to G protein-coupled EP1-4 receptors (EP1 to Gq, EP2,4 to Gs, and EP3 to Gi/o).
Amaia Nazabal   +2 more
doaj   +1 more source

Preparing Excitable Cardiac Papillary Muscle and Cardiac Slices for Functional Analyses

open access: yesFrontiers in Physiology, 2022
While the reductionist approach has been fruitful in understanding the molecular basis of muscle function, intact excitable muscle preparations are still important as experimental model systems.
Bradley M. Palmer, Stephen P. Bell
doaj   +1 more source

Dynamic Learning Framework for Smooth-Aided Machine-Learning-Based Backbone Traffic Forecasts

open access: yesSensors, 2022
Recently, there has been an increasing need for new applications and services such as big data, blockchains, vehicle-to-everything (V2X), the Internet of things, 5G, and beyond.
Mohamed Khalafalla Hassan   +7 more
doaj   +1 more source

Parametric Surface Modelling for Tea Leaf Point Cloud Based on Non-Uniform Rational Basis Spline Technique

open access: yesSensors, 2021
Plant leaf 3D architecture changes during growth and shows sensitive response to environmental stresses. In recent years, acquisition and segmentation methods of leaf point cloud developed rapidly, but 3D modelling leaf point clouds has not gained much ...
Wenchao Wu, Yongguang Hu, Yongzong Lu
doaj   +1 more source

Cannabigerol modulates α2-adrenoceptor and 5-HT1A receptor-mediated electrophysiological effects on dorsal raphe nucleus and locus coeruleus neurons and anxiety behavior in rat

open access: yesFrontiers in Pharmacology, 2023
The pharmacological profile of cannabigerol (CBG), which acid form constitutes the main precursor of the most abundant cannabinoids, has been scarcely studied. It has been reported to target α2-adrenoceptor and 5-HT1A receptor.
Aitziber Mendiguren   +5 more
doaj   +1 more source

Functional characterization of cannabidiol effect on the serotonergic neurons of the dorsal raphe nucleus in rat brain slices

open access: yesFrontiers in Pharmacology, 2022
Cannabidiol (CBD), the main non-psychoactive cannabinoid found in the cannabis plant, elicits several pharmacological effects via the 5-HT1A receptor. The dorsal raphe nucleus (DRN) is the main serotonergic cluster in the brain that expresses the 5-HT1A ...
Aitziber Mendiguren   +4 more
doaj   +1 more source

Specialization slicing [PDF]

open access: yesProceedings of the 35th ACM SIGPLAN Conference on Programming Language Design and Implementation, 2014
This paper defines a new variant of program slicing, called specialization slicing , and presents an algorithm for the specialization-slicing problem that creates an optimal output slice. An algorithm for specialization slicing is polyvariant : for a given procedure р, the algorithm may ...
Min Aung   +3 more
openaire   +1 more source

Assertion-based slicing and slice graphs [PDF]

open access: yesFormal Aspects of Computing, 2010
AbstractThis paper revisits the idea of slicing programs based on their axiomatic semantics, rather than using criteria based on control/data dependencies. We show how the forward propagation of preconditions and the backward propagation of postconditions can be combined in a new slicing algorithm that is more precise than the existing specification ...
Barros, José Bernardo   +3 more
openaire   +5 more sources

History Slicing

open access: yes2011 26th IEEE/ACM International Conference on Automated Software Engineering (ASE 2011), 2011
This material is based upon work supported by the National Science Foundation under award CCF-1116943, and by a Google Faculty Research Award.
Francisco Servant, James A Jones
openaire   +2 more sources

Unions of slices are not slices [PDF]

open access: yesSeventh European Conference onSoftware Maintenance and Reengineering, 2003. Proceedings., 2003
Many approaches to slicing rely upon the 'fact' that the union of two static slices is a valid slice. It is known that static slices constructed using program dependence graph algorithms are valid slices (Reps and Yang, 1988). However, this is not true for other forms of slicing. For example, it has been established that the union of two dynamic slices
DE LUCIA, Andrea   +3 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy