Results 121 to 130 of about 197,902 (248)

A 3D Human Neuron‐on‐Chip Platform to Monitor Neuronal Injury Responses

Advanced Healthcare Materials, EarlyView.
This study presents a novel 3D Neuron‐on‐Chip model that can maintain human PSC‐derived excitatory prefrontal cortex neurons in 3D hydrogels and can be used to monitor neuronal injury responses over time. Results show injury‐induced acute neuronal excitotoxicity, declining neuronal connectivity, and the activation of a neurodegenerative, SASP‐like ...
Ruiping Tang, Charles‐Francois Latchoumane, Avi Chopra, Md Marzan Sarkar, Chunki Kim, Nathan Gonsalves, Hsueh‐Fu Wu, John C. Sentmanat, Alan Liu, Isha Mhatre‐Winters, Aditya Mishra, Andrei G. Fedorov, Jay M. Patel, Nadja Zeltner, Steven L. Stice, Jason R. Richardson, Lohitash Karumbaiah   +16 more
wiley   +1 more source

Computed Tomography slice interpolation in the longitudinal direction based on deep learning techniques: To reduce slice thickness or slice increment without dose increase. [PDF]

PLoS One, 2022
Wu S, Nakao M, Imanishi K, Nakamura M, Mizowaki T, Matsuda T.   +5 more
europepmc   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

The value of using a deep learning image reconstruction algorithm of thinner slice thickness to balance the image noise and spatial resolution in low-dose abdominal CT. [PDF]

Quant Imaging Med Surg, 2023
Wang H, Li X, Wang T, Li J, Sun T, Chen L, Cheng Y, Jia X, Niu X, Guo J.   +9 more
europepmc   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

The impact of MRI slice thickness on the detection of spinal syndesmophytes in axial spondyloarthritis. [PDF]

Arthritis Res Ther
Klavdianou K, Abrar DB, Mewes AD, Tsiami S, Sewerin P, Baraliakos X.   +5 more
europepmc   +1 more source

Impact of slice thickness, pixel size, and CT dose on the performance of automatic contouring algorithms. [PDF]

J Appl Clin Med Phys, 2021
Huang K, Rhee DJ, Ger R, Layman R, Yang J, Cardenas CE, Court LE.   +6 more
europepmc   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Influence of slice thickness on computed tomography perfusion-derived ischemic core volume accuracy in acute ischemic stroke. [PDF]

Quant Imaging Med Surg
Otgonbaatar C, Song H, Jung KH, Hwang I, Yun TJ, Sohn CH.   +5 more
europepmc   +1 more source

Robustness of radiomic features in CT images with different slice thickness, comparing liver tumour and muscle. [PDF]

Sci Rep, 2021
Escudero Sanchez L, Rundo L, Gill AB, Hoare M, Mendes Serrao E, Sala E.   +5 more
europepmc   +1 more source