Results 51 to 60 of about 223,441 (320)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Coordinate Singularities in Harmonically-sliced Cosmologies [PDF]

open access: yes, 2000
Harmonic slicing has in recent years become a standard way of prescribing the lapse function in numerical simulations of general relativity. However, as was first noticed by Alcubierre (1997), numerical solutions generated using this slicing condition ...
A. Geyer   +13 more
core   +2 more sources

Slicing Abstractions

open access: yes, 2007
Summary: Abstraction and slicing are both techniques for reducing the size of the state space to be inspected during verification. In this paper, we present a new model checking procedure for infinite-state concurrent systems that interleaves automatic abstraction refinement, which splits states according to new predicates obtained by Craig ...
Brückner, I   +3 more
openaire   +4 more sources

Optimal Discrete Slicing [PDF]

open access: yesACM Transactions on Graphics, 2017
Slicing is the procedure necessary to prepare a shape for layered manufacturing. There are degrees of freedom in this process, such as the starting point of the slicing sequence and the thickness of each slice. The choice of these parameters influences the manufacturing process and its result: The number of slices significantly affects the time needed ...
Alexa, Marc   +2 more
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

High aspect ratio grooving of Si using a wet etching assisted by wire-friction (A feasibility study for the applicaiotn for slicing Si ingots)

open access: yesNihon Kikai Gakkai ronbunshu, 2014
Silicon (Si) wafers for electronic or photovoltaic devices are fabricated by slicing a Si ingot using mechanical slicing with a diamond wire. Recently, the slicing method without generating damage on Si surface has been strongly required because of the ...
Junji MURATA   +3 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Microbiological Quality of Sausage during Slicing at Food Retail Stores in Shiraz, Iran [PDF]

open access: yesInternational Journal of Nutrition Sciences, 2017
Background: Sausage can become contaminated via the environment, handlers, and equipment particularly slicing machines and cutting utensils during processing.
Mohammad Hassan Ehrampoush   +6 more
doaj  

Slicing of silicon into sheet material. Silicon sheet growth development for the large area silicon sheet task of the low cost silicon solar array project [PDF]

open access: yes, 1977
Fabrication of a prototype large capacity multiple blade slurry saw is considered. Design of the bladehead which will tension up to 1000 blades, and cut a 45 cm long silicon ingot as large as 12 cm in diameter is given.
Fleming, J. R., Holden, S. C.
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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