Results 51 to 60 of about 53,899 (312)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

A trajectory-based strict semantics for program slicing

, 2010
We define a program semantics that is preserved by dependence-based slicing algorithms. It is a natural extension, to non-terminating programs, of the semantics introduced by Weiser (which only considered terminating ones) and, as such, is an accurate ...
Kiss, A, Laurence, Mike, Lahcen Ouarbya, Laurence, MR, Mike Laurence, Harman, Mark, Robert M. Hierons, Sebastian Danicic, Harman, M, Hierons, Robert M., Kiss, Ákos, Binkley, D, Laurence, Michael, Danicic, S, Hierons, Robert, David Binkley, Barraclough, RW, Mark Harman, Barraclough, Richard W., Barraclough, Richard, Ouarbya, Lahcen, Hierons, RM, Ouarbya, L, Richard W. Barraclough, Ákos Kiss, Danicic, Sebastian, Binkley, David   +26 more
core   +1 more source

Slicing-volume: hybrid 3D/2D multi-target selection technique for dense virtual environments [PDF]

, 2020
3D selection in dense VR environments (e.g., point clouds) is extremely challenging due to occlusion and imprecise mid-air input modalities (e.g., 3D controllers and hand gestures). In this paper, we propose "Slicing-Volume", a hybrid selection technique
Roberto Antonio Montano Murillo (4466572), Sriram Subramanian (4466416), Stephen DiVerdi (16280582), Rubaiat Habib Kazi (16280579), Diego Martinez Plasencia (4466698), Cuong Nguyen (4592824)   +5 more
core   +2 more sources

Extracting Apis dorsata Binghamii Honey using Incision Technique

International Journal of Agriculture System, 2015
At the time of the flowering season arrives, honey bee colonies will actively fill the nest with honey, pollen and puppies. Along with the honey gatherers are also actively seeking to take the honey bee hive. Honeycomb (Apis dorsata Binghami) which has a
Rosmarlinasiah Rosmarlinasiah, Sitti Marwah, Meisanti Meisanti   +2 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Data dependencies and program slicing: from syntax to abstract semantics

, 2008
We discuss the relation between program slicing and data dependencies. We claim that slicing can be defined, and therefore calculated, parametrically on the chosen notion of dependency, which implies a different result when building the program ...
Damiano Zanardini, MASTROENI, Isabella, Isabella Mastroeni, Mastroieni, Isabella, Zanardini, Damiano   +4 more
core   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Streaming and Elastic Traffic Service in 5G-Sliced Wireless Networks and Mutual Utilization of Guaranteed Resource Units

Future Internet
Researchers of 5G-sliced Wireless Networks are faced with the task of achieving, at the same time, (i) mandatory isolation among network slices and (ii) the effective utilization of resource at Fifth Generation Base Station (gNB).
Yves Adou, Ekaterina Markova, Yuliya Gaidamaka   +2 more
doaj   +1 more source

High aspect ratio grooving of Si using a wet etching assisted by wire-friction (A feasibility study for the applicaiotn for slicing Si ingots)

Nihon Kikai Gakkai ronbunshu, 2014
Silicon (Si) wafers for electronic or photovoltaic devices are fabricated by slicing a Si ingot using mechanical slicing with a diamond wire. Recently, the slicing method without generating damage on Si surface has been strongly required because of the ...
Junji MURATA, Takeshi TSUCHIDA, Yasuhiro TANI, Yu ZHANG   +3 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source