Results 61 to 70 of about 2,031,344 (242)
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
, 1978 sealskin n...he tells this story about how he got the pair of swileskin slippers that he's been wearin' now for nigh on thirty years (of course he's had three new pair of soles and two new pair of uppers in 'em durin' that time, but they're the ...
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Calyptraeotheres camposi Ayón-Parente & Hendrickx, 2014, sp. nov. [PDF]
, 2014 Calyptraeotheres camposi sp. nov. (Figs. 1–3) Material examined. Holotype: ovigerous female (CL= 3.1 mm; CW= 3.6 mm) (EMU- 10361), off El Huizache, Sinaloa, 22 ° 59 ' 43 ''N, 106 ° 15 ' 37 ''W, 31 m, trawl, 1 August 2009.
Hendrickx, Michel E. +1 more
core +1 more source
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
FEBS Open Bio, EarlyView.Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Black cloth embroidered slippers, ca.1880-1900 [PDF]
, 1880 This pair of men's black cloth slippers feature multi-colored hand-embroidered flowers. They were worn by a member of the family of Elizabeth Low Curtis, born 1892 in Seattle.1 Slipper; Materials: fabric; Dimensions: 2.25 in.H x 3.25 in.W x 10.25 in.
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FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
, 1988 sealskin n..where else [but Water Street] could you select a pair of Eskimo-made sealskin boots out of an odoriferous barrel?PRINTED ITEM SUPJUN 10 1988 WKG. M.
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GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source