Results 21 to 30 of about 16,576 (267)
Neurobiology of Disease, 2013 Triose phosphate isomerase (TPI) is responsible for the interconversion of dihydroxyacetone phosphate to glyceraldehyde-3-phosphate in glycolysis. Point mutations in this gene are associated with a glycolytic enzymopathy called TPI deficiency. This study
Stacy L. Hrizo +5 more
doaj +1 more source
Moisturizers: The slippery road
Indian Journal of Dermatology, 2016 Moisturizers are an important part of a dermatologist's armamentarium although little is written and well, a less is truly known about them. There is a cornucopia of projected skin products in the market whose real scientific role is not proven. These products although at times are regarded as mere cosmetics but have a well-known role in many skin ...
Anisha Sethi +3 more
openaire +3 more sources
Destabilizing Bodies, Destabilizing Disciplines: Practicing Liminality in Music Therapy
Voices, 2014 Our project began with a consideration of how disability studies might enrich the practice of music therapy. Originally, we were interested in how a greater awareness of disability issues might help music therapists, especially because of the often ...
Cindy LaCom, Rachel Reed
doaj +1 more source
Climbers for Bat Conservation: creating a citizen science program in Red River Gorge Kentucky
Frontiers in Communication, 2023 In recent years, North American bat populations have been presented with new conservation threats including white-nose syndrome. As these threats continue to impact bats it is important to locate and study these populations.
Emily E. Gross +4 more
doaj +1 more source
Psychedelics and neonihilism: connectedness in a meaningless world
Frontiers in Psychology, 2023 The resurgence of psychedelic research explicitly targets treating mental health conditions largely through psychedelics-assisted psychotherapy. Current theories about mechanisms of change in psychedelics-assisted psychotherapy focus on mystical ...
Patric Plesa, Rotem Petranker
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
THE SLIPPERY SLOPE OF CONCESSION [PDF]
Economic Inquiry, 2009 We show that with common knowledge and a common rate of time preference, the potential loser can always avoid wasteful conflict through a time‐consistent series of small concessions. We examine how the failure of each of these assumptions may explain why conflicts arise. We also debate which actions may be helpful in such unfortunate circumstances.
Jack Hirshleifer +2 more
openaire +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source