Results 41 to 50 of about 193,029 (302)

Model for the function of Dscam1-Robo1-Slit-N signaling in longitudinal axon guidance.

open access: yes, 2016
Slit is expressed by midline glia at the CNS midline and likely processed after secretion. Slit-N can form a complex with Dscam1 and Robo1 to promote longitudinal axon growth.
Thomas Kidd (446223)   +9 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Amontillado is required for Drosophila Slit processing and for tendon-mediated muscle patterning

open access: yesBiology Open, 2016
Slit cleavage into N-terminal and C-terminal polypeptides is essential for restricting the range of Slit activity. Although the Slit cleavage site has been characterized previously and is evolutionally conserved, the identity of the protease that cleaves
Elly Ordan, Talila Volk
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Effect of slit length on linear and non-linear acoustic transfer impedance of a micro-slit plate

open access: yesActa Acustica, 2022
The effect of the slit length on the acoustic transfer impedance of micro-slit plates (MSPs) is investigated in the linear and non-linear regime for a specific slit geometry.
Aulitto Alessia   +3 more
doaj   +1 more source

The Merli-Missiroli-Pozzi Two-Slit Electron Interference Experiment [PDF]

open access: yes, 2008
In 2002 the readers of the scientific magazine 'Physics World' voted Young's double-slit experiment applied to the interference of single electrons to be 'the most beautiful experiment in physics'; this experiment, in truth, had already been carried out ...
Rosa, Rodolfo
core  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Slit Lamp Biomicroscopy

open access: yesMedEdPORTAL, 2012
This resource is a video showing ocular examination techniques utilizing slit lamp biomicroscopy. It has been distributed to first-year ophthalmology residents at our institution as part of their orientation.
William Randolph Morris
doaj   +1 more source

Changes in type 2 innate lymphoid cells and serum cytokines in sublingual immunotherapy in pediatric patients with allergic rhinitis

open access: yesBMC Pediatrics, 2023
Background Type 2 innate lymphoid cells (ILC2) are upregulated in childhood allergic rhinitis (AR) and are associated with AR severity. This study aimed to investigate changes in the ILC2 milieu in pediatric patients with AR after sublingual ...
Xiaoqiang Wang   +4 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

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