Results 121 to 130 of about 119,393 (311)

Boosting Organic Long Persistent Luminescence by Enhancing Charge Separation Processes in Three‐Component Systems

open access: yesAdvanced Science, EarlyView.
Electron donor TMB is introduced into BF2bdk‐PhB system to enhance charge separation process. The resultant three‐component materials exhibit visible‐light‐excitable OLPL afterglow lasting for several hours under ambient environment, with OLPL efficiency of ≈10% and display OLPL brightness comparable to inorganic materials.
Zi Ye   +6 more
wiley   +1 more source

The Detection of Spontaneous Venous Pulsation with Smartphone Video Ophthalmoscopy

open access: yesClinical Ophthalmology, 2020
Charlotte Laurent,1,2 Sheng Chiong Hong,3,4 Kirsten R Cheyne,2 Kelechi C Ogbuehi2 1Ophthalmology Department, Southern District Health Board, Dunedin, New Zealand; 2University of Otago, Dunedin, New Zealand; 3Ophthalmology Department, Mid Central District
Laurent C   +3 more
doaj  

Aligned Conductive Magnetic Nanofibers with Directional Magnetic Field Stimulation Promotes Peripheral Nerve Regeneration

open access: yesAdvanced Science, EarlyView.
Peripheral nerve injury necessitates alternatives to autografts. This study combines magnetic nanoparticles, oriented PCL fibers, and Ppy to create a conductive, magnetically active scaffold. In vitro and in vivo experiments demonstrated enhanced downstream pathways of calcium signaling, as revealed by transcriptome analysis.
Zheyuan Fan   +4 more
wiley   +1 more source

Parvalbumin Interneuron‐Dependent Hippocampal Neurogenesis Evoked by Prolonged Rhythmic Light Flicker

open access: yesAdvanced Science, EarlyView.
This study demonstrates that prolonged rhythmic 40 Hz light flicker enhances spatial learning by stimulating PV interneuron‐dependent neurogenesis. The light flicker selectively activates PV interneurons, which enhances GABAergic support for the integration of immature neurons in the adult dentate gyrus.
Hai Yan   +16 more
wiley   +1 more source

Splicing Shift of RAC1 Accelerates Tumorigenesis and Defines a Potent Therapeutic Target in Lung Cancer

open access: yesAdvanced Science, EarlyView.
Dysregulated RNA splicing is an underappreciated molecular feature of cancer. By integrating murine and cellular models with patient specimens of lung adenocarcinoma, this study demonstrates that RAC1B, rather than RAC1A isoform, promotes tumorigenesis and presents a potent therapeutic target for lung cancer. Mechanistically, RAC1B preferentially binds
Yueren Yan   +19 more
wiley   +1 more source

Hexokinase‐2 as a Therapeutic Target: Alleviating Herpes Simplex Keratitis Through Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Herpes Simplex Virus Type 1 (HSV‐1) infection triggers metabolic reprogramming in corneal cells, shifting from mitochondrial respiration to aerobic glycolysis with marked upregulation of Hexokinase‐2 (HK2). This study identifies HK2 as a therapeutic target: inhibiting HK2 with lonidamine significantly reduces viral replication and promotes corneal ...
Dan Jiang   +9 more
wiley   +1 more source

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