From actually toxic to highly specific – novel drugs against poxviruses [PDF]
The potential use of variola virus, the causative agent of smallpox, as a bioweapon and the endemic presence of monkeypox virus in Africa demonstrate the need for better therapies for orthopoxvirus infections. Chemotherapeutic approaches to control viral
Schnierle Barbara, Sliva Katja
doaj +3 more sources
Research and Development of Laser Engraving and Material Cutting Machine from 3D Printer [PDF]
This article deals with the adjustment of a 3D printer for laser engraving and material cutting. The print head can be fitted with a solid laser diode module, which achieves a compact size while retaining its useful power.
Durna Antonin +4 more
doaj +2 more sources
The Main Therapeutic Applications of Cannabidiol (CBD) and Its Potential Effects on Aging with Respect to Alzheimer’s Disease [PDF]
The use of cannabinoids (substances contained specifically in hemp plants) for therapeutic purposes has received increased attention in recent years.
Václav Trojan +4 more
doaj +2 more sources
Inosine Pranobex Deserves Attention as a Potential Immunomodulator to Achieve Early Alteration of the COVID-19 Disease Course [PDF]
Since its licensing in 1971, the synthetic compound inosine pranobex has been effectively combating viral infections, including herpes zoster, varicella, measles, and infections caused by the herpes simplex virus, human papillomavirus, Epstein–Barr virus,
Jiří Beran +2 more
doaj +2 more sources
The potential dangers of whooping cough: a case of rib fracture and pneumothorax [PDF]
Background Pertussis, also known as whooping cough, is an acute respiratory illness primarily caused by Bordetella pertussis. Highly contagious, it poses significant morbidity and mortality risks, especially in infants.
Petra Zatovkaňuková, Jiří Slíva
doaj +2 more sources
Evaluating Drug Interaction Risks: Nirmatrelvir & Ritonavir Combination (PAXLOVID®) with Concomitant Medications in Real-World Clinical Settings [PDF]
Background: This research article delves into the battle against the COVID-19 pandemic, focusing on the efficacy and, particularly, the safety of the combination of nirmatrelvir with ritonavir, which is found in the pharmaceutical product Paxlovid®. This
Petra Zatovkaňuková +2 more
doaj +2 more sources
Dynamic Responses of a Single-Axle Trailer When Driving Over a Road Obstacle [PDF]
Trailers for passenger cars are often used for the transportation of goods. There are various trailer designs. Most trailers are equipped with axles, which include swinging arms and are suspended by rubber segments.
Dalibor Barta +5 more
doaj +2 more sources
The use of NATO Evaluation Tools for the Assessment of the Czech Land and Air Forces Preparedness
The article deals with the method of application of evaluation tools, applicable for the evaluation of the preparedness assessment of undeclared headquarters and units of the Czech Armed Forces.
Petr Slíva, Tomáš Špok
doaj +1 more source
Usporedba metodologija za određivanje velikih voda na odabranim slivovima u Bosni i Hercegovini
U radu su korištene neke od uobičajenih hidroloških metoda te hidrološki model EBA4SUB kojima su određene vrijednosti maksimalnih protoka raznih povratnih razdoblja za tri sliva u Bosni i Hercegovini.
Andrea Petroselli +2 more
doaj +1 more source
Vaccination directed against the human endogenous retrovirus-K envelope protein inhibits tumor growth in a murine model system [PDF]
Human endogenous retrovirus (HERV) genomes are chromosomally integrated in all cells of an individual. They are normally transcriptionally silenced and transmitted only vertically. Enhanced expression of HERV-K accompanied by the emergence of anti-HERV-K-
Büchner, Sarah M. +6 more
core +9 more sources

