Results 171 to 180 of about 1,049,594 (310)
Effect of Tibial Slope on Knee Mechanics for Posterior Cruciate Ligament Deficient Cruciate-retaining Total Knee Arthroplasty. [PDF]
Olson A +5 more
europepmc +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Comparison of Methods for Incorporating Related Data When Developing Clinical Prediction Models: A Simulation Study. [PDF]
Elayan H +6 more
europepmc +1 more source
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
GIS-based multi-criteria landslide susceptibility assessment in the Northwestern Himalaya, Jammu and Kashmir, India. [PDF]
Jasrotia AS +6 more
europepmc +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Millet cultivation mitigates soil erosion in sloping farmland by regulating near-soil surface traits. [PDF]
Yao C +8 more
europepmc +1 more source
This paper generalises the physical dependence of the relationship between contributing area, local slope, and the surface soil grading using a pedogenesis model and allows an exploration of soilscape self-organisation. A parametric study was carried out
Garry R. Willgoose (21281153) +3 more
core
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source

