Results 81 to 90 of about 1,176,662 (241)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Macrobenthic ecology of the West Shetland Slope

open access: yes, 2000
An unusual and complex hydrographic regime in the Faeroe-Shetland Channel makes it one of the best-studied oceanographic provinces in the world. However, few benthic ecological studies of the region have been undertaken since the early 1880s. The present
Narayanaswamy, B.E.
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Raninfall and Slope Characteristics Affecting Soil Erosion on Hillsopes

open access: yes, 2010
A soil erosion model including interrill erosion and rill erosion was developed for hillslope. The rainfall and slope characteristics affecting soil erosion on hillslopes was analyzed by simulation.
刘青泉
core   +2 more sources

Effect of Slope Gradient on the Process of Runoff and Sediment Yield and Water-Sediment Relation on the Loess Slope

open access: yesShuitu baochi yanjiu, 2020
In order to explore the effect of slope gradient on erosion and water-sediment relationship on the loess slope under a rainfall event, simulated rainfall experiments were carried out in the laboratory, and the water-sediment relationship on the loess ...
SU Yuanyi   +6 more
doaj  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Optimal designs for estimating the slope of a regression [PDF]

open access: yes
In the common linear regression model we consider the problem of designing experiments for estimating the slope of the expected response in a regression.
Dette, Holger, Melas, Viatcheslav B.
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Instability of blanket bog slopes on Cuilcagh Mountain, N.W. Ireland [PDF]

open access: yes
There are many accounts of slope failures on blanket bogs, but their nature and controls are poorly understood. This study investigates the mechanisms of blanket bog failure on Cuilcagh Mountain, north-west Ireland, and identifies the critical factors ...
Kirk, Kathleen Jane
core   +3 more sources

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