Results 141 to 150 of about 213,923 (293)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz +9 more
wiley +1 more source
, 2010 Rainfall-induced debris flows involving ash-fall pyroclastic deposits covering steep mountain slopes that surround the Somma-Vesuvius volcano, are natural events representing the main cause of risk for urban settlements located at footslopes.
Napolitano, Elisabetta
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CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
Aplicação da teoria do equilíbrio-limite na análise de estabilidade de taludes: estudo de caso [PDF]
, 2014 TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Filosofia e Ciências Humanas. Geologia.Instabilidades em taludes são responsáveis por grandes impactos negativos em obras de engenharia, devendo ser obtido um bom conhecimento das ...
Ecks, Jonathan
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Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Slope-stability assessments using finite-element limit-analysis methods
This paper utilizes finite-element limit-analysis methods to investigate the stability of slopes of various properties and in nature. Specifically, a slope with a soft (weak material) band, a postquake slope, and rock slopes were investigated.
A. Schmid (21276497) +3 more
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Critical assessment of existing slope stability formulae and application to slope stabilisation
, 2012 In this research, extensive use has been made of limit equilibrium methods of analysis for studying the stability of slopes. For the determination of the factor of safety (FOS) of slopes, the usual two-step process has been adopted; (a) assuming a slip ...
Firat, Seyhan
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Slope stability in unsaturated soils [PDF]
, 1976 This thesis deals with the analysis of slope stability in unsaturated soils. The failure criterion (Mohr-Coulomb) is extended to take into account the effect of a second stress variable (i.e., matrix suction).
Widger, Robert Allan
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source