Results 151 to 160 of about 117,118 (314)
PGC-1a in muscle links metabolism to inflammation [PDF]
, 2009 1. In higher eukaryotes, metabolism and immunity are tightly coupled. However, whereas in evolutionary terms, a compromised immune response due to undernourishment has been the predominant problem, the inflammatory response to obesity and other life ...
Handschin, C.
core
The Embryonic Development of the Cotylean Polyclad Phrikoceros jannetae
Acta Zoologica, EarlyView.ABSTRACT Polyclads exhibit distinct developmental modes ranging from direct to indirect development, with several transitional stages also recognised. The existence of an indirect developmental mode in polyclads with a planktonic life history stage in the form of a free‐swimming larva is unique among all free‐living flatworms and makes polyclads a ...
Mehrez Gammoudi +6 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Obesity is a chronic, relapsing, multisystem disease in which cardiometabolic risk arises from excess adiposity and progressive dysfunction of peripheral organs, ultimately disrupting endocrine and metabolic crosstalk among tissues. Within this network, sulphur‐based biology, centred on hydrogen sulphide and related reactive sulphur species, has ...
Martina Smimmo +4 more
wiley +1 more source
Piperine enhances contractile force in slow- and fast-twitch muscle [PDF]
: Piperine has been shown to bind to myosin and shift the distribution of conformational states of myosin molecules from the super-relaxed state to the disordered relaxed state.
Ørtenblad, Niels; id_orcid +4 more
core +1 more source
The FEBS Journal, EarlyView.Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna +5 more
wiley +1 more source
Effects of oxidation in the power of chemically skinned rat soleus fibres [PDF]
, 2010 Oxidation alters calcium sensitivity, and decreases maximum isometric force (Po) and shortening velocity (Vmax) of single muscle fibres. To examine the effect of oxidation on the curvature of the force-velocity relationship, which determines muscle power
Rittweger, Jörn +3 more
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Scientific ReportsSkeletal muscles are classified into slow-twitch muscles composed primarily of type I and IIa fibers with high oxidative metabolism, and fast-twitch muscles composed of type IIx and IIb fibers with high glycolytic metabolism.
Hiroki Hamaguchi +5 more
doaj +1 more source
The epigenetic landscape of skeletal muscle in response to exercise and aging
The FEBS Journal, EarlyView.Epigenetic mechanisms regulate gene expression in response to exercise and aging, thereby supporting skeletal muscle plasticity. Acute exercise induces chromatin remodeling through histone modifications and DNA methylation, promoting the expression of exercise‐responsive genes.
Sabrina Champsi, David A. Hood
wiley +1 more source
The FEBS Journal, EarlyView.Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki +7 more
wiley +1 more source