Results 51 to 60 of about 2,280,950 (106)

Two novel mouse models of slow-wave-sleep enhancement in aging and Alzheimer's disease [PDF]

, 2022
Aging and Alzheimer's disease (AD) are both associated with reduced quantity and quality of the deepest stage of sleep, called slow-wave-sleep (SWS). Slow-wave-sleep deficits have been shown to worsen AD symptoms and prevent healthy aging.
Ogbeide-Latario, Oghomwen E, Gompf, Heinrich S, Ferrari, Loris L, Anaclet, Christelle   +3 more
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The Roles of Cortical Slow Waves in Synaptic Plasticity and Memory Consolidation

Frontiers in Neural Circuits, 2017
Sleep plays important roles in sensory and motor memory consolidation. Sleep oscillations, reflecting neural population activity, involve the reactivation of learning-related neurons and regulate synaptic strength and, thereby affect memory consolidation.
Daisuke Miyamoto, Daisuke Miyamoto, Daichi Hirai, Masanori Murayama   +3 more
doaj   +1 more source

The Alzheimer’s Pathways Sleep Study (ALPS): an experimental randomized controlled trial to improve cognition and Alzheimer’s pathophysiology through slow-wave sleep

Trials
Background Slow-wave activity (0.5–4 Hz electroencephalographic activity) during non-rapid eye movement sleep is consistently associated with better cognitive performance in older adults.
Yue C. Dong, Rima F. Habte, Kibra M. Dessa, Mary E. Fletcher, Angela M. Ianni, Brian J. Lopresti, Howard J. Aizenstein, Ann D. Cohen, Thomas K. Karikari, Andrea M. Weinstein, Marie Anne Gebara, Meredith L. Wallace, Daniel J. Buysse, Kristine A. Wilckens   +13 more
doaj   +1 more source

The promise of portable remote auditory stimulation tools to enhance slow-wave sleep and prevent cognitive decline. [PDF]

, 2023
Dementia is the seventh leading cause of mortality, and a major source of disability and dependency in older individuals globally. Cognitive decline (and, to a lesser extent, normal ageing) are associated with sleep fragmentation and loss of slow-wave ...
Klöppel, Stefan, Stefan Klöppel, Marc A. Züst, Céline J. Zeller, Wunderlin, Marina, Christoph Nissen, Zeller, Céline J, Züst, Marc A, Nissen, Christoph, Marina Wunderlin   +9 more
core   +2 more sources

Better quality sleep promotes daytime physical activity in patients with chronic pain? : A multilevel analysis of the within-person relationship [PDF]

, 2014
Background: Promoting physical activity is key to the management of chronic pain, but little is understood about the factors facilitating an individual’s engagement in physical activity on a day-to-day basis. This study examined the within-person effect
Tang Nicole K. Y., Nicole K Y Tang, Sanborn Adam N., Nicole K. Y. Tang, Nicole K. Y. Tang (542290), Adam N. Sanborn (542291), Adam N Sanborn, Tang, Nicole K. Y., Adam N. Sanborn, Sanborn, Adam N.   +9 more
core   +2 more sources

Polysomnographically mediated cognitive improvements in individuals with insomnia symptoms following continuous theta-burst stimulation of the default mode network

Frontiers in Sleep
IntroductionInsomnia is associated with mild cognitive impairment, although the mechanisms of this impairment are not well-understood. Timing of slow-wave and rapid eye movement sleep may help explain cognitive impairments common in insomnia.
Alisa Huskey, Julia M. Fisher, Lindsey Hildebrand, David Negelspach, Kymberly Henderson-Arredondo, Samantha Jankowski, Salma I. Patel, Ying-Hui Chou, Natalie S. Dailey, William D. S. Killgore   +9 more
doaj   +1 more source

Automated analysis of a large-scale paediatric dataset illustrates the interdependent relationship between epilepsy and sleep

Scientific Reports, 2023
Slow waves are an electrophysiological characteristic of non-rapid eye movement sleep and a marker of the restorative function of sleep. In certain pathological conditions, such as different types of epilepsy, slow-wave sleep is affected by epileptiform ...
Jelena Skorucak, Bigna K. Bölsterli, Sarah Storz, Sven Leach, Bernhard Schmitt, Georgia Ramantani, Reto Huber   +6 more
doaj   +1 more source

A hypothetic aging pathway from skin to hypothalamic suprachiasmatic nucleus via slow wave sleep

Sleep Science, 2016
Many observations have demonstrated that the hypothalamic neuroendocrine change determines the chronological sequence of aging in mammals. However, it remains uncertain on the mechanism to account for the hypothalamic aging manifestations.
Zi-Jian Cai
doaj   +1 more source

Slow waves during deep sleep support cardiac function

Current Issues in Sport Science
Introduction The role of sleep in cardiovascular health, particularly the impact of deep non-rapid eye movement (NREM) sleep, is gaining interest in the prevention of cardiovascular diseases (Grandner et al., 2016).
Stephanie Huwiler, Manuel Carro-Domínguez, Fabia Stich, Rossella Sala, Florent Aziri, Anna Trippel, Tabea Ryf, Susanne Markendorf, David Niederseer, Philipp Bohm, Gloria Stoll, Lily Laubscher, Jeivicaa Thevan, Christina M. Spengler, Joanna Gawinecka, Elena Osto, Reto Huber, Nicole Wenderoth, Christian Schmied, Caroline Lustenberger   +19 more
doaj   +1 more source

Alzheimer’s disease genetic risk and sleep phenotypes: association with more slow-waves and daytime sleepiness [PDF]

, 2020
peer reviewedStudy objectives: Sleep disturbances and genetic variants have been identified as risk factors for Alzheimer's disease. Our goal was to assess whether genome-wide polygenic risk scores (PRS) for AD associate with sleep phenotypes in young ...
Koshmanova, Ekaterina, Salmon, Eric, Jaspar, Mathieu , Berthomier, Christian, Meyer, Christelle, Brandewinder, Marie , Muto, Vincenzo, Ahariz, Naïma, Luxen, André, Georges, Michel, Maquet, Pierre, Phillips, Christophe, Hammad, Grégory, Archer, Simon N., Van Egroo, Maxime, Brandewinder, Marie, Jaspar, Mathieu, Byrne, Enda , Mouraux, Charlotte , Ghaemmaghami, Pouya, Collette, Fabienne, Mouraux, Charlotte, Yengo, Loic, Chylinski, Daphné, Berthomier, Christina, Elansary, Mahmoud, Archer,  Simon N, Archer, Simon N, Visscher, Peter M, Ghaemmaghami Tabrizi, Pouya, Schmidt, Christina, Meyer, Christelle , Visscher, Peter M., Coppieters, Wouter, Berthomier, Christian , Degueldre, Christian, Vandewalle, Gilles, Byrne, Enda, Dijk, Derk-Jan, Ghaemmaghami, Pouya    +39 more
core   +1 more source