Results 51 to 60 of about 9,671 (264)

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Slow Earthquakes: Tremor, Low-frequency Earthquakes and Slow Slip Events

, 2022
Thesis (Ph.D.)--University of Washington, 2022The focus of this thesis is slow earthquakes, that is earthquake-like events that release energy over a period of hours to months, rather than the seconds to minutes characteristic of a typical earthquake ...
Ducellier, Ariane
core  

Experimental Evaluation of 100Cr6 Steel Microindented Surfaces Under Lubricated Nonconformal Point Contacts

Advanced Engineering Materials, EarlyView.
The tribological behavior of 100Cr6 steel spheres textured via Vickers microindentation is evaluated under lubricated sliding by varying both dimple size and density. Fine and dense textures significantly reduce friction across all lubrication regimes, while large dimples increase it.
Farideh Davoodi, Pasquale Guglielmi, Gianfranco Palumbo, Giuseppe Carbone   +3 more
wiley   +1 more source

Cascading rupture of patches of high seismic energy release controls the growth process of episodic tremor and slip events

Earth, Planets and Space, 2021
Slip phenomena on plate interfaces reflect the heterogeneous physical properties of the slip plane and, thus, exhibit a wide variety of slip velocities and rupture propagation behaviors.
Keita Nakamoto, Yoshihiro Hiramatsu, Takahiko Uchide, Kazutoshi Imanishi   +3 more
doaj   +1 more source

Enhancing Strength and Electrical Conductivity in Al–Zr–Sc Conductor Alloys Through Sn and Sr Microalloying and Two‐Step Aging Treatment

Advanced Engineering Materials, EarlyView.
Trace additions of Sn and Sr combined with a two‐step aging treatment are shown to enhance the microstructure and performance of Al–Zr–Sc conductor alloys. Strength and electrical conductivity increase concurrently through accelerated precipitation of fine Al3(Sc, Zr) precipitates and improved dislocation resistance, offering a cost‐effective pathway ...
Quan Shao, Emad M. Elgallad, Alexandre Maltais, X.‐Grant Chen   +3 more
wiley   +1 more source

Defining the Relationship between Seismicity and Deformation at Regional and Local Scales [PDF]

, 2013
In this thesis, I use source inversion methods to improve understanding of crustal deformation along the Nyainquentanglha (NQTL) Detachment in Southern Tibet and the Piceance Basin in northwestern Colorado.
Williams, Nneka Njeri Akosua
core   +1 more source

Assessment of S-net seafloor pressure data quality in view of seafloor geodesy

Progress in Earth and Planetary Science, 2022
Long-term continuous observation of seafloor pressure is effective for detecting seafloor vertical deformations that are associated with transient tectonic phenomena such as slow slip events.
Ryota Hino, Tatsuya Kubota, Naotaka Y. Chikasada, Yusaku Ohta, Hideto Otsuka   +4 more
doaj   +1 more source

Low‐Angle Grain Boundaries and Re‐Segregation in Single‐Crystalline Ni‐Base Superalloys

Advanced Engineering Materials, EarlyView.
This work demonstrates that Re‐segregation at low‐angle grain boundaries (LAGBs) in Ni‐base superalloys is influenced by misorientation angle. Advanced microscopy and atom probe tomography reveal that higher misorientation angles increases Re‐segregation.
Alireza B. Parsa, Aparna Saksena, Alesander Kostka, Pascal Thome, Felicitas Scholz, Alexandre Mussi, Christoph Somsen, Baptiste Gault, Jan Frenzel, Gunther Eggeler   +9 more
wiley   +1 more source

Towards Defect Phase Diagrams: From Research Data Management to Automated Workflows

Advanced Engineering Materials, EarlyView.
A research data management infrastructure is presented for the systematic integration of heterogeneous experimental and simulation data required for defect phase diagrams. The approach combines openBIS with a companion application for large‐object storage, automated metadata extraction, provenance tracking and federated data access, thereby supporting ...
Khalil Rejiba, Sang‐Hyeok Lee, Christina Gasper, Martina Freund, Sandra Korte‐Kerzel, Ulrich Kerzel   +5 more
wiley   +1 more source

Slow slip events in Mexico: A historical perspective

Tectonophysics
This paper introduces a historical catalogue of slow slip events (SSE) for the Mexican subduction zone. The catalogue incorporates all 25 SSEs recorded since they were discovered in 1997. The inversion of GPS data for ten SSEs in Guerrero and five in Oaxaca reveals a clear slow slip segmentation along the Middle America Trench, with slip maxima between
Víctor M. Cruz-Atienza, Sara Franco, Vladimir Kostoglodov, Josué Tago, Ekaterina Kazachkina, Jorge Real, Carlos Villafuerte, Raymundo Plata-Martinez   +7 more
openaire   +1 more source