Results 31 to 40 of about 7,578,938 (178)

Effects of Cortical Cooling on Activity Across Layers of the Rat Barrel Cortex

Frontiers in Systems Neuroscience, 2020
Moderate cortical cooling is known to suppress slow oscillations and to evoke persistent cortical activity. However, the cooling-induced changes in electrical activity across cortical layers remain largely unknown.
Gulshat Burkhanova, Kseniya Chernova, Roustem Khazipov, Roustem Khazipov, Maxim Sheroziya   +4 more
doaj   +1 more source

Decoupling of sleep-dependent cortical and hippocampal interactions in a neurodevelopmental model of schizophrenia [PDF]

, 2012
Rhythmic neural network activity patterns are defining features of sleep, but interdependencies between limbic and cortical oscillations at different frequencies and their functional roles have not been fully resolved.
Tricklebank, Mark, Tricklebank, Mark D., Bartsch, Ullrich, Jones, Matt W, Wafford, Keith, Tricklebank, Mark D, Edgar, Dale, Phillips, Keith G., McCarthy, Andrew, Wafford, Keith A., Phillips, K, Jones, Matt W., Edgar, Dale M., McCarthy, Andrew P, Edgar, DM, Wafford, KA, Phillips, Keith, McCarthy, Andrew P., Jones, ME   +18 more
core   +1 more source

EEG characteristics of anti ⁃ leucine ⁃ rich glioma ⁃ inactivated 1 antibody ⁃ associated encephalitis

Chinese Journal of Contemporary Neurology and Neurosurgery, 2023
Objective To summarize the clinical and EEG characteristics of anti ⁃ leucine ⁃ rich glioma⁃inactivated 1 (LGI1) antibody⁃associated encephalitis. Methods and Results The clinical data and EEG characteristics of 27 patients diagnosed with anti⁃LGI1 ...
ZHANG Yi⁃fan, SHI Wei⁃xiong, LIU Xiao, WANG Qun   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Deep sleep slow wave–spindle coupling is selectively linked to plasma amyloid-β levels in older adults in clinical trials

Scientific Reports
Slow wave activity, the signature of deep/slow wave sleep, has consistently been linked to amyloid-beta (Aβ), a biomarker of neurodegeneration. Less is known about how Aβ relates to specific microstructural processes within slow wave sleep, such as the ...
Marina Wunderlin, Korian Wicki, Charlotte Elisabeth Teunissen, Marc Alain Züst   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Gating and the Need for Sleep: Dissociable Effects of Adenosine A1 and A2A Receptors

Frontiers in Neuroscience, 2019
Roughly one-third of the human lifetime is spent in sleep, yet the reason for sleep remains unclear. Understanding the physiologic function of sleep is crucial toward establishing optimal health.
Michael Lazarus, Yo Oishi, Theresa E. Bjorness, Theresa E. Bjorness, Robert W. Greene, Robert W. Greene, Robert W. Greene   +6 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Contribution of transcranial oscillatory stimulation to research on neural networks: An emphasis on hippocampo-neocortical rhythms

Frontiers in Human Neuroscience, 2013
EEG rhythms reflect the synchronized activity of underlying biological neuronal network oscillations, and certain predominant frequencies are typically linked to certain behavioral states.
Lisa eMarshall, Sonja eBinder
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source