Results 231 to 240 of about 189,686 (299)

The Feasibility of a Chair Yoga Intervention to Improve Mental Health and Wellbeing for Adults With Learning Disabilities: A Pilot Study

open access: yesBritish Journal of Learning Disabilities, EarlyView.
ABSTRACT Background Yoga has been shown to have physical benefits for people with learning disabilities. It is unclear whether the mental health and wellbeing benefits of yoga found in other populations are apparent in people with learning disabilities. This study was a pilot. Method The study comprised three stages.
Dale Metcalfe   +3 more
wiley   +1 more source

Matsupexole: A novel nonergot dopamine receptor agonist with sustained efficacy in a rat model of Parkinson's disease and limited off‐target activity

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Dopamine receptor agonists, particularly targeting the dopamine D2L receptor (D2LR), have been used to treat Parkinson's disease (PD). However, valvular heart disease and somnolence, mainly caused by activating the serotonin 5‐HT2B receptor (5‐HT2BR) and dopamine D3 receptor (D3R), respectively, currently challenge their clinical
Takayuki Suzuki   +4 more
wiley   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

open access: yesBiological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning   +19 more
wiley   +1 more source

Closed-loop auditory stimulation of slow-wave sleep in chronic insomnia: a pilot study. [PDF]

open access: yesJ Sleep Res
Dudysová D   +9 more
europepmc   +1 more source

Expansion of the Phenotypic and Genotypic Spectrum for PRKAR1B‐Related Marbach–Schaaf Neurodevelopmental Syndrome: A Case Series

open access: yesClinical Genetics, EarlyView.
Comprehensive clinical description of 12 subjects with pathogenic PRKAR1B variants, including two heterozygous deletions supporting haploinsufficiency as a possible mechanism of disease, providing valuable insight into the pathophysiology of MASNS and setting a framework upon which to design future mechanistic studies of PKA signaling in brain ...
Sebastian Burkart   +17 more
wiley   +1 more source

Relational Bleeding, Bending, and Diffraction: Brazilian Transnational Children's Transgressive Digital Play on Roblox

open access: yesChildren &Society, EarlyView.
ABSTRACT This article draws from a one‐year connective ethnographic study that examined Brazilian transnational children's composing practices on a digital gaming platform named Roblox. Building upon research on digital childhoods, transnational childhoods, and play, the authors thought with concepts of relational bleeding, bending, and diffraction to ...
Mariana Lima Becker, Alex Corbitt
wiley   +1 more source

Correlation of slow-wave sleep with motor and nonmotor progression in Parkinson's disease. [PDF]

open access: yesAnn Clin Transl Neurol
Chen J   +11 more
europepmc   +1 more source

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