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Recent research has found that the human sleep cycle is characterised by changes in spatiotemporal patterns of brain activity. Yet, we are still missing a mechanistic explanation of the local neuronal dynamics underlying these changes.
Beatrice M. Jobst +8 more
doaj +1 more source
Neurostimulation techniques to enhance sleep and improve cognition in aging
Sleep plays a critical role in the process of memory consolidation. In particular, during non-rapid eye movement (NREM) slow wave sleep, slow-oscillations, spindles, hippocampal sharp wave ripples, and their phase coupling are involved in the process of ...
Daniela Grimaldi +3 more
doaj +1 more source
Thalamic influence on slow wave slope renormalization during sleep [PDF]
OBJECTIVE Slow waves are thought to mediate an overall reduction in synaptic strength during sleep. The specific contribution of the thalamus to this so-called synaptic renormalization is unknown. Thalamic stroke is associated with daytime sleepiness,
Aleksandra K. Eberhard‐Moscicka +22 more
core +2 more sources
Enhancement of sleep slow waves: underlying mechanisms and practical consequences.
Even modest sleep restriction, especially the loss of sleep slow wave activity, is invariably associated with slower EEG activity during wake, the occurrence of local sleep in an otherwise awake brain, and impaired performance due to cognitive and memory
Michele eBellesi +5 more
doaj +1 more source
Sleep disorders are one of the significant problems in the modern society. Current research is on the lookout for the nonpharmacological ways to improve sleep quality and slow wave brain activity that plays a crucial role in homeostasis and cognitive ...
A.N. Puchkova +8 more
doaj +1 more source
Exercise improves the quality of slow-wave sleep by increasing slow-wave stability
Exercise can improve sleep by reducing sleep latency and increasing slow-wave sleep (SWS). Some studies, however, report adverse effects of exercise on sleep architecture, possibly due to a wide variety of experimental conditions used.
Insung Park +11 more
doaj +1 more source
IntroductionMillions of people worldwide take medications such as L-DOPA that increase dopamine to treat Parkinson’s disease. Yet, we do not fully understand how L-DOPA affects sleep and memory.
Hanna K. Isotalus +23 more
doaj +1 more source
Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias +3 more
wiley +1 more source
Frontal grey matter microstructure is associated with sleep slow waves characteristics in late midlife [PDF]
STUDY OBJECTIVES: The ability to generate slow waves (SW) during non-rapid eye movement (NREM) sleep decreases as early as the 5 th decade of life, predominantly over frontal regions.
Salmon, Eric +25 more
core +1 more source
ABSTRACT Background We aimed to identify the proportion of individuals with a confirmed diagnosis of childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE) who show a negative routine EEG (rEEG), and to determine the main factors associated with this finding.
Francesco Fortunato +7 more
wiley +1 more source

