Results 151 to 160 of about 6,925,642 (276)

Hydrodynamic stability of slowly varying flows [PDF]

open access: yes
First the classical Taylor problem of fluid rotating between two concentric cylinders is considered. A method of approximating to the curve of neutral stability is developed.
Eames, K. A.
core  

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

An Explicit Factorization of the Green's Function for an Acoustic Half‐Space Problem with Impedance Boundary Conditions into an Oscillatory Exponential and a Slowly Varying Function

open access: yes
In this paper, new representations of the Green's function for an acoustic ‐dimensional half‐space problem with impedance boundary conditions are presented.
Melenk, Jens Markus; orcid:   +5 more
core   +1 more source

Complex Slowly Varying Functions

open access: yes
Title: Complex Slowly Varying Functions Abstract: Classical Karamata theory formalizes asymptotic scale invariance on the positive realline under the minimal baseline of measurability. Past extensions to the complex planehave largely circumvented the topological foundation by imposing a priori holomorphyand vanishing logarithmic derivatives (𝑧𝑓 ...
openaire   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

open access: yesFEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

open access: yesFEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page   +4 more
wiley   +1 more source

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