Results 221 to 230 of about 74,948 (341)

Continuous emergence of phototaxis in Dictyostelium discoideum. [PDF]

open access: yesPLoS One
Genettais D   +4 more
europepmc   +1 more source

Lab‐Scale Continuous Biomanufacturing: A Tool for Process Development With Adaptive Strategies for Capture and Virus Inactivation

open access: yesBiotechnology and Bioengineering, EarlyView.
Schematic representation of the continuous lab‐scale process. ABSTRACT Monoclonal antibodies (mAbs) are nowadays fundamental in treating a wide range of severe diseases, including cancer, infections, or autoimmune disorders. Due to their high specificity, potent activity, and fewer side effects compared to small molecular drugs, the market for mAbs is ...
Thomas Kruse   +5 more
wiley   +1 more source

Engineered Bacterial Ligand From Streptococcus pneumoniae on Macroporous Resins for Selective Affinity Capture of Secretory IgA

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Secretory immunoglobulin A (sIgA) is a promising emerging biopharmaceutical candidate, but it currently lacks a standardized platform for purification. To address this, a novel affinity chromatography resin was developed by immobilizing protein variants of the Streptococcus pneumoniae surface protein, SpsA, as an affinity ligand.
David Scheich   +8 more
wiley   +1 more source

Defect‐engineered iron single‐site catalysts with tailored atomic coordination for enhanced mild photothermal therapy via triad modulation of apoptosis and ferroptosis

open access: yesBMEMat, EarlyView.
A defect‐engineered triad catalyst (DMOF‐SNP‐siRNA) has been developed to enhance mild photothermal therapy for cancer treatment by addressing the limitations of heat shock protein overexpression and suboptimal therapeutic outcomes. This synergy induces potent apoptotic and ferroptotic responses, significantly enhancing the photothermal and catalytic ...
Fanghua Zhang   +9 more
wiley   +1 more source

Injuries in deep time: interpreting competitive behaviours in extinct reptiles via palaeopathology

open access: yesBiological Reviews, EarlyView.
ABSTRACT For over a century, palaeopathology has been used as a tool for understanding evolution, disease in past communities and populations, and to interpret behaviour of extinct taxa. Physical traumas in particular have frequently been the justification for interpretations about aggressive and even competitive behaviours in extinct taxa.
Maximilian Scott   +3 more
wiley   +1 more source

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