Reducing bias in open-label trials where blinded outcome assessment is not feasible: strategies from two randomised trials [PDF]
Background Blinded outcome assessment is recommended in open-label trials to reduce bias, however it is not always feasible. It is therefore important to find other means of reducing bias in these scenarios.
A Dechartres +29 more
core +2 more sources
An improved method of delivering a sclerosing agent for the treatment of malignant pleural effusion
Background Malignant pleural effusion (MPE) is a devastating sequela associated with cancer. Talc pleurodesis is a common treatment strategy for MPE but has been estimated to be unsuccessful in up to 20–50% of patients.
Tim N. Beck +8 more
doaj +1 more source
Application Method of Antimicrobial Substances for the Control of Schizophyllum Commune Fr. Causing Brown Germ and Seed Rot of Oil Palm [PDF]
Biological seed treatment promotes to save the environment from toxic chemicals in the agricultural practices. Schizophyllum commune is one of the important seedborne pathogenic fungi causing brown germ and seed rot of oil palm which required effective ...
Dikin, A. (Antario) +2 more
core +4 more sources
Comparison of side effects of oxytetracycline and talc pleurodesis: an experimental study
Background Chemical pleurodesis is widely recommended in the treatment of refractory pleural effusion or pulmonary air leak of different etiologies. Although several agents have been used, many questions have remained unanswered about their toxicity ...
Kavaklı Kuthan +7 more
doaj +1 more source
Background: Autologous blood is a novel, high-efficacy sclerosant for treatment of malignant pleural effusion (MPE), similar to tetracycline. There has been no comparative data between autologous blood and a worldwide sclerosant like talc.
Warangkana Keeratichananont +2 more
doaj +1 more source
The evidence on the effectiveness of management for malignant pleural effusion: a systematic review.
The aim of this study was to review systematically the available evidence on pleurodesis for malignant effusion, focusing on the choice of the agents, route of delivery and other strategies to improve outcomes. Four electronic databases (MEDLINE, EMBASE,
Browne, John +4 more
core +1 more source
Elucidating the crystal-chemistry of Jbel Rhassoul stevensite (Morocco) by advanced analytical techniques [PDF]
The composition of Rhassoul clay is controversial regarding the nature of the puremineral clay fraction which is claimed to be stevensite rather than saponite.
A. Maazouz +28 more
core +3 more sources
Influence of Talc Dose on Extrapleural Talc Dissemination after Talc Pleurodesis
This study was designed to ascertain, in a rabbit model, extrapleural talc deposition and the related inflammatory response after talc slurry pleurodesis with two clinical doses, 200 and 50 mg/kg. Histopathologic evaluations revealed that whereas numerous rabbits receiving a high dose had talc in the ipsilateral (70%) and contralateral (55%) lung ...
Montes Castillo, Juan Francisco +5 more
openaire +3 more sources
OBJETIVO: A pleurodese é uma alternativa eficaz no controle dos derrames pleurais malignos, mas existem controvérsias a respeito de sua indicação e técnica.
Evaldo Marchi +5 more
doaj +1 more source
P70 Talc slurry pleurodesis: does mixing talc with 50% dextrose rather than normal saline increase success rate? [PDF]
Introduction Symptomatic malignant pleural effusions can be managed effectively with talc pleurodesis. Various studies document the success rate for talc pleurodesis around 80%. In these studies, talc was mixed with normal saline to make the slurry prior to pleurodesis.
A. Khanna, C. Mackinlay, A. Kerry
openaire +1 more source

