Results 201 to 210 of about 47,311 (284)

Adipose‐derived small extracellular vesicles exacerbate microvascular dysfunction in heart failure with preserved ejection fraction via mmu‐miR‐582‐3p‐mediated Rap1b suppression

open access: yesInterdisciplinary Medicine, EarlyView.
This study reveals that small extracellular vesicles (sEVs) from visceral fat compromise coronary microcirculation in a mouse model of heart failure with preserved ejection fraction (HFpEF). The SGLT2 inhibitor canagliflozin emerges as a therapeutic strategy, improving cardiac function and endothelial health.
Lu Chen   +12 more
wiley   +1 more source

Mapping developmental transitions in mental health from mid‐ to late‐adolescence: Concurrent and longitudinal links to cognition

open access: yesJCPP Advances, EarlyView.
Abstract Background Developmental changes in mental health are mostly mapped between childhood and adolescence or childhood and adulthood. This study maps developmental transitions in mental health profiles from mid‐ to late‐adolescence, exploring how these transitions relate to cognitive function in mid‐adolescence. Method Participants from the IMAGEN
Silvana Mareva   +24 more
wiley   +1 more source

In Vitro Evaluation of Novel Calcium Silicate‐Based and Resin‐Modified Calcium Silicate Materials: Cytocompatibility and Mineralization Potential on Human Dental Pulp Stem Cells for Pulp Repair

open access: yesMicroscopy Research and Technique, EarlyView.
This study demonstrates that Biodentine XP exhibits superior cytocompatibility, promotes odontogenic differentiation, and enhances mineralization in human dental pulp stem cells, supporting its use in regenerative endodontics. Resin‐modified materials showed lower bioactivity, highlighting the importance of material composition in pulp therapy outcomes.
Francisco Javier Rodríguez‐Lozano   +5 more
wiley   +1 more source

Changing Practices in Axillary Surgery After Neoadjuvant Breast Cancer Therapy: Insights From the EUSOMA European Database

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Introduction Sentinel lymph node biopsy (SLNB) after neoadjuvant treatment (NAT) is an increasing option for axillary surgery in patients responding to treatment, whether diagnosed as clinically node‐negative (cN0) or node‐positive (cN + ). This study evaluates SLNB trends in patients with NAT in a large European population.
Antonio J. Esgueva   +49 more
wiley   +1 more source

Ultra-depleted mantle source of basalts from the South Pole-Aitken basin. [PDF]

open access: yesNature
Zhou Q   +17 more
europepmc   +1 more source

Associations between health care access and posttraumatic stress disorder symptoms among rural and urban lesbian, gay, bisexual, transgender, and queer adults

open access: yesJournal of Traumatic Stress, EarlyView.
Abstract Lesbian, gay, bisexual, transgender, and queer (LGBTQ+) individuals experience elevated rates of trauma exposure, minority stress, and posttraumatic stress disorder (PTSD). Yet, research examining how geographic location and LGBTQ+ identity shape PTSD outcomes is scant, particularly studies considering structural facilitators and barriers ...
Emily A. Kenyon   +6 more
wiley   +1 more source

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