Results 71 to 80 of about 599,791 (275)

Sedimentary provenance in the southern sector of the São Francisco Basin, SE Brazil

Brazilian Journal of Geology
: We present new Sm-Nd, U-Pb and Hf isotope geochronological data for the siliciclastic rocks in the southern sector of the São Francisco Basin. An abrupt change in the Sm-Nd data is observed from the Carrancas Formation’s oligomitic conglomerates (TDM ...
Gustavo Macedo de Paula-Santos, Marly Babinski   +1 more
doaj   +1 more source

Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery

Advanced Science, EarlyView.
Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae, Jisun Lee, Jae‐Hun Ahn, Hosam Choi, Huijeong Choi, Jungmin Kim, Minho Kang, Ho Rim Oh, So Hyun Park, Eun Young Oh, Sanghyuk Jeon, Yeeun Lee, Yu‐Sun Lee, Na‐Young Lee, Hee‐Jin Bae, Jina Kwak, Jooil Kim, Nakyung Lee, Beomsun Kang, Ji‐Hye Kim, Eunsaem Song, Daesub Song, Hyunho Yoon, Sang‐Myeong Lee, Hyewon Youn, Kiyoun Lee, Byeong‐Cheol Kang, Jae‐Hwan Nam   +27 more
wiley   +1 more source

Блоки доордовикских пород в структуре Платиноносного пояса Урала: Sm-Nd изотопный возраст дунит-клинопироксенит-тылаитового комплекса массива Денежкин Камень

Литосфера, 2019
По 14 валовым пробам и 4 фракциям клинопироксена Sm-Nd методом датирован разрез стратифицированного блока дунит-клинопироксенит-тылаитового комплекса (горячего меланжа) в структуре массива Денежкин Камень.

doaj  

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

Advanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer, Ian de Ridder, Mahjoobeh Ehsani, Marasim Khan, Justin Kale, Lukas P. Frenzel, David Andrews, Spyridoula Karamanou, Ana J. Garcia‐Saez, Geert Bultynck   +9 more
wiley   +1 more source

Progress and Prospect of Sm-Fe-N Magnets

Inorganics
High-performance but expensive neodymium-iron-boron (Nd-Fe-B) magnets are widely used in automotive and electrical applications. Prospective candidates for rare-earth-free magnets include Fe-based magnets such as L10-FeNi and α″-Fe16N2 phase.
Tetsuji Saito
doaj   +1 more source

(Table S1) Nd and Sm isotopic data for samples from ODP Hole 145-886C

, 2008
(Table S1) Nd and Sm isotopic data for samples from ODP Hole 145 ...
MacLeod, Kenneth G, Susanna W Blair (7914797), Kenneth G MacLeod (6961271), Ellen E Martin (6962390), Martin, Ellen E, Blair, Susanna W   +5 more
core   +1 more source

Magnetoelectric Nanoparticles Enable Modulation of Cortical Networks by Low‐Intensity Static Magnetic Fields In Vitro

Advanced Science, EarlyView.
Neuromodulation strategies are increasingly needed to stimulate, restore, or replace altered neuronal activity in disease. Cobalt ferrite‐barium titanate (CFO–BTO) magnetoelectric nanoparticles convert low‐intensity static magnetic fields into local electrical modulation of cortical networks.
Nathalia Cancino‐Fuentes, Alejandro Suarez‐Perez, Elric Zhang, Hao Ye, Marta Bonato, Joana Covelo, Vitaly Pustovalov, Anton Guimera‐Brunet, Xavi Illa, Valentin Gantenbein, Cagatay M. Oral, Marta Parazzini, Salvador Pané, Maria V. Sanchez‐Vives   +13 more
wiley   +1 more source

Influence of Thermal Treatment on the Chemical and Structural Properties of Geopolymer Gels Doped with Nd₂O₃ and Sm₂O₃

Gels
In this research, the influence of the thermal treatment of geopolymer gels at 300 °C, 600 °C and 900 °C when incorporated with 5% rare earth elements (REEs) in the form of (GP-Sm) Sm2O3 and (GP-Nd) Nd2O3 was investigated.
Miloš Nenadović, Sanja Knežević, Marija Ivanović, Snežana Nenadović, Danilo Kisić, Maja Popović, Jelena Potočnik   +6 more
doaj   +1 more source

(Table S1) Nd and Sm isotopic data for samples from ODP Hole 171B-1050C

, 2008
(Table S1) Nd and Sm isotopic data for samples from ODP Hole 171B ...
MacLeod, Kenneth G, Susanna W Blair (7914797), Kenneth G MacLeod (6961271), Ellen E Martin (6962390), Martin, Ellen E, Blair, Susanna W   +5 more
core   +1 more source

B Cells are Activated via a Nanoporous Interface that Stabilizes Microvilli and Engages Mechanosensitive Ion Channels

Advanced Science, EarlyView.
B cells can be activated independently of antigen recognition via mechanical stimulation through nanoporous substrates. Exposure to such substrates induced B cell microvilli extension into the pores, intracellular Ca2+ signaling, phosphorylation of signaling proteins, and CD69 expression.
Nozie D. Aghaizu, Willi Weber, Nadine Strempel, Asya Polat, Enrico Klotzsch   +4 more
wiley   +1 more source