Results 91 to 100 of about 8,011,267 (345)
Permanent Scatterer Interferometry (PSI) has been used to detect and characterize the subsidence of the Pisa urban area, which extends for 33 km2 within the Arno coastal plain (Tuscany, Italy).
Lorenzo Solari+4 more
doaj +1 more source
A multi-source approach to determine SMA incidence and research ready population
In spinal muscular atrophy (SMA), degeneration of motor neurons causes progressive muscular weakness, which is caused by homozygous deletion of the SMN1 gene.
I. Verhaart+8 more
semanticscholar +1 more source
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan+10 more
wiley +1 more source
Recent translational research developments in Spinal Muscular Atrophy (SMA), outcome measure design and demands from regulatory authorities require that clinical outcome assessments are ‘fit for purpose’.
D. Ramsey+25 more
semanticscholar +1 more source
Characterization of a New SMA Actuator
AbstractIn this work, we propose the design and characterization of a new shape memory alloy actuator based on a slider and slot mechanism. The device is composed by two couples of opposed SMA coil elements. The SMA elements are heated by means of Joule effect connecting their ends to an electric power supply through special terminal clips.
BORBONI, Alberto, FAGLIA, Rodolfo
openaire +3 more sources
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez+3 more
wiley +1 more source
Distribution and Morphologies of Transverse Aeolian Ridges in ExoMars 2020 Rover Landing Site
Aeolian processes are believed to play a major role in the landscape evolution of Mars. Investigations on Martian aeolian landforms such as ripples, transverse aeolian ridges (TARs), and dunes, and aeolian sediment flux measurements are important to ...
Anshuman Bhardwaj+3 more
doaj +1 more source
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring+6 more
wiley +1 more source
Assessing the Sensitivity of the OMI-NO2 Product to Emission Changes across Europe
The advent of satellite data has provided a source of independent information to monitor trends in tropospheric nitrogen dioxide levels. To interpret these trends, one needs to know the sensitivity of the satellite retrieved NO2 column to anthropogenic ...
Renske Timmermans+5 more
doaj +1 more source
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke+2 more
wiley +1 more source