Results 111 to 120 of about 8,011,267 (345)
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
Orphanet Journal of Rare Diseases, 2017 BackgroundThe aim of this study was to determine the economic burden and health-related quality of life (HRQOL) of patients with Spinal Muscular Atrophy (SMA) and their caregivers in Spain.MethodsThis was a cross-sectional and retrospective study of ...
J. López‐Bastida +5 more
semanticscholar +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Willingness to take COVID-19 vaccination in low-income countries: Evidence from Ethiopia
PLoS ONE, 2022 Background In low-income countries, vaccination campaigns are lagging, and evidence on vaccine acceptance, a crucial public health planning input, remains scant.
Christoph Strupat +3 more
doaj
Evaluation of VIIRS and MODIS Thermal Emissive Band Calibration Stability Using Ground Target
Remote Sensing, 2016 The S-NPP Visible Infrared Imaging Radiometer Suite (VIIRS) instrument, a polar orbiting Earth remote sensing instrument built using a strong MODIS background, employs a similarly designed on-board calibrating source—a V-grooved blackbody for the Thermal
Sriharsha Madhavan +4 more
doaj +1 more source
, 2018 : This paper aims to evaluate potential of an Fe-based shape memory alloy (Fe-SMA) for strengthening civil structures. Mechanical properties of the Fe-SMA were investigated with a direct tensile test, which showed the stress-induced transformation ...
Kinam Hong +3 more
semanticscholar +1 more source
Molecular Therapy, 2015 Spinal muscular atrophy (SMA) is the most frequent lethal genetic neurodegenerative disorder in infants. The disease is caused by low abundance of the survival of motor neuron (SMN) protein leading to motor neuron degeneration and progressive paralysis ...
K. Meyer +13 more
semanticscholar +1 more source
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source