Results 111 to 120 of about 9,380,370 (380)

Calorimetric study of the nematic to smectic-A phase transition in octylcyanobiphenyl-hexane binary mixtures

, 2010
The continuous nematic to smectic-A (N-SmA) phase transition has been studied by high-resolution ac-calorimetry in binary mixtures of the liquid crystal octylcyanobiphenyl(8CB) and a non-mesogenic, low-molecular weight, solvent n-hexane(hex) as a ...
Germano S. Iannacchione, Krishna P. Sigdel, P. G. de Gennes, S. Chandrasekhar   +3 more
core   +1 more source

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

FEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

SMA - TREATMENT [PDF]

Neuromuscular Disorders, 2021
S. Owen, D. Šoltić, S. Synowsky, E. Crompton, R. Yáñez-Muñoz, B. Schneider, H. Shorrock, S. Shirran, T. Gillingwater, M. Bowerman, H. Fuller   +10 more
  +9 more sources

Power regulation of variable speed multi rotor wind systems using fuzzy cascaded control

Scientific Reports
Power quality is a crucial determinant for integrating wind energy into the electrical grid. This integration necessitates compliance with certain standards and levels.
Habib Benbouhenni, Ilhami Colak, Nicu Bizon, Mohamed I. Mosaad, Teshome Goa Tella   +4 more
doaj   +1 more source

A conserved inhibitory interdomain interaction regulates DNA-binding activities of hybrid two-component systems in Bacteroides

mBio
Hybrid two-component systems (HTCSs) comprise a major class of transcription regulators of polysaccharide utilization genes in Bacteroides. Distinct from classical two-component systems in which signal transduction is carried out by intermolecular ...
Rong Gao, Ti Wu, Ann M. Stock
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Enabling high-throughput enzyme discovery and engineering with a low-cost, robot-assisted pipeline

Scientific Reports
As genomic databases expand and artificial intelligence tools advance, there is a growing demand for efficient characterization of large numbers of proteins.
Brenna Norton-Baker, Mackenzie C. R. Denton, Natasha P. Murphy, Benjamin Fram, Samuel Lim, Erika Erickson, Nicholas P. Gauthier, Gregg T. Beckham   +7 more
doaj   +1 more source

Unsaturated fatty acid perturbation combats emerging triazole antifungal resistance in the human fungal pathogen Aspergillus fumigatus

mBio
Contemporary antifungal therapies utilized to treat filamentous fungal infections are inhibited by intrinsic and emerging drug resistance. Consequently, there is an urgent need to develop novel antifungal compounds that are effective against drug ...
Cecilia Gutierrez-Perez, Charles Puerner, Jane T. Jones, Sandeep Vellanki, Elisa M. Vesely, Mark A. Xatse, Andre F. C. Viera, Carissa P. Olsen, Keren O. Attiku, Steven Cardinale, Steven M. Kwasny, Narendran G-Dayanandan, Timothy J. Opperman, Robert A. Cramer   +13 more
doaj   +1 more source

Explanation and Evaluation of the Knowledge Creation Input Pattern in Higher Education [PDF]

مطالعات مدیریت راهبردی, 2015
This study aims to identify and prioritize individual factors (as inputs) affecting the Knowledge Creationof the faculty members at Tehran University, has been designed and implemented.
Seyed Mohammad Mirkamali, Mohammad Reza Hamidizadeh, Abbas Bazargan Harandi, Fatemeh Narenji Thani   +3 more
doaj  

Explicit finite element implementation of a shape memory alloy constitutive model and associated analyses [PDF]

, 2017
Shape memory alloys (SMA) represent an important class of smart metallic materials employed in various innovative applications thanks to their unique thermomechanical behavior.
Auricchio, F., Boatti, E., Ferraro, M., Hartl, D.J., Mercuri, V., Scalet, G.   +5 more
core