Results 121 to 130 of about 9,380,370 (380)

Spliceosome integrity is defective in the motor neuron diseases ALS and SMA [PDF]

open access: gold, 2012
Hitomi Tsuiji   +11 more
openalex   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

The asymptotic solutions for the motion of a charged symmetric gyrostat in the irrational frequency case

open access: yesScientific Reports
The primary objective of this study is to explore the spatial rotary movements of a symmetrically charged rigid body (RB) that is rotating around a fixed point, akin to Lagrange’s scenario as a novel scenario where its center of mass experiences a slight
T. S. Amer   +3 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Estimating the relative importance of epidemiological and behavioural parameters for epidemic mpox transmission: a modelling study

open access: yesBMC Medicine
Background Many European countries experienced outbreaks of mpox in 2022, and there was an mpox outbreak in 2023 in the Democratic Republic of Congo. There were many apparent differences between these outbreaks and previous outbreaks of mpox; the recent ...
Madhav Chaturvedi   +6 more
doaj   +1 more source

Analysis of hybrid woven fabrics with shape memory alloys wires embedded [PDF]

open access: yes, 2010
Until recently, Shape Memory Alloys (SMAs) were predominantly developed for applications in the biomedical and engineering industry, and only a limited number of applications in textiles are known. Fabrics made of natural fibres (e. g.
Ciesielska-Wrobel, Izabela   +3 more
core  

SMA AT THE CROSSROADS [PDF]

open access: yesMedical Anthropology Quarterly, 1983
The following editorial was prepared by Dr. Charles C. Hughes, Immediate Past President of the Society for Medical Anthropology. In it, Dr. Hughes summarizes the discussion to date surrounding the proposed reorganization of the American Anthropological Association, and the ways in which this reorganization will affect the Society.
openaire   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

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