Results 131 to 140 of about 8,994,995 (387)

Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis. [PDF]

, 2016
Cytochrome P450 (CYP) monooxygenases epoxidize the omega-3 polyunsaturated fatty acid (PUFA) docosahexaenoic acid into novel epoxydocosapentaenoic acids (EDPs) that have multiple biological actions.
Hammock, Bruce D, Hye Khan, Md Abdul, Imig, John D, Lee, Kin Sing Stephen, Levick, Scott P, Sharma, Amit   +5 more
core   +3 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

SMA CLINICAL DATA [PDF]

Neuromuscular Disorders, 2021
Eva Vrščaj, Damjan Osredkar, Laurent Servais, Tamara Dangouloff   +3 more
openaire   +7 more sources

Explicit finite element implementation of a shape memory alloy constitutive model and associated analyses [PDF]

, 2017
Shape memory alloys (SMA) represent an important class of smart metallic materials employed in various innovative applications thanks to their unique thermomechanical behavior.
Auricchio, F., Boatti, E., Ferraro, M., Hartl, D.J., Mercuri, V., Scalet, G.   +5 more
core  

Calorimetric study of the nematic to smectic-A phase transition in octylcyanobiphenyl-hexane binary mixtures

, 2010
The continuous nematic to smectic-A (N-SmA) phase transition has been studied by high-resolution ac-calorimetry in binary mixtures of the liquid crystal octylcyanobiphenyl(8CB) and a non-mesogenic, low-molecular weight, solvent n-hexane(hex) as a ...
Germano S. Iannacchione, Krishna P. Sigdel, P. G. de Gennes, S. Chandrasekhar   +3 more
core   +1 more source

Structural correlates of semantic and phonemic fluency ability in first and second languages [PDF]

, 2009
Category and letter fluency tasks are commonly used clinically to investigate the semantic and phonological processes central to speech production, but the neural correlates of these processes are difficult to establish with functional neuroimaging ...
A. Grogan, Abutalebi, Alario, Baldo, Bialystok, Billingsley, Booth, C. J. Price, Costafreda, Crinion, Crosson, Crosson, D. W. Green, Damasio, Desmond, Elfgren, FIEZ, Friederici, Garrard, Gourovitch, Henry, Hodges, HODGES, J. T. Crinion, Lee, Leggio, Mari  n, Martin, McCarthy, Mechelli, Molinari, Moretti, Mummery, N. Ali, Paulesu, Paulesu, Perani, Perani, Petrides, Phelps, Pihlajam  ki, Richter, Robles, Rosselli, Rosser, Rueckert, Schlosser, Schwartz, Schwartz, Tettamanti, Tricomi, Troyer, Ullman, Watkins   +53 more
core   +2 more sources

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

Insights on the concept of indicator populations derived from parentage‐based tagging in a large‐scale coho salmon application in British Columbia, Canada

Ecology and Evolution, 2020
For Pacific salmon, the key fisheries management goal in British Columbia (BC) is to maintain and restore healthy and diverse Pacific salmon populations, making conservation of salmon biodiversity the highest priority for resource management decision ...
Terry D. Beacham, Colin Wallace, Kim Jonsen, Brenda McIntosh, John R. Candy, David Willis, Cheryl Lynch, Ruth E. Withler   +7 more
doaj   +1 more source

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

FEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling, Kodi Hunter, Celest W. S. Tay, Nicola T. Wood, Philip Cohen   +4 more
wiley   +1 more source