Results 161 to 170 of about 11,247,349 (328)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Caldasia, 2004 The mouthpart deformities of chironomid larvae are considered as indicators ofenvironmental stress caused by water pollution such as heavy metals, pesticides, butas well by organic contamination.
RISS WOLFGANG +2 more
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One small leap for the jumping spider but a giant step for vision science [PDF]
, 2009 Robert R. Jackson, Duane P. Harland
openalex +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Caldasia, 1989 Mediante los lineamientos metodológicos de la escuela Zurich-Montpellier (Braun-Blanquet, 1979) se realizaron 102 levantamientos de la vegetación que se establece en los pantanos, turberas o depósitos turbosos de los páramos de los alrededores de Bogotá.
Sánchez M. Roberto +2 more
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Caldasia, 1982 A new microteiid species is described from two sites in Colombia's Orinoco River Basin near the eastern border with Venezuela. The other Colombian Leposoma species have leaf-shaped dorsal scales, but in the new taxon they are keeled, elongate and ...
Ayala Stephen C., Harris Dennis M.
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