Results 11 to 20 of about 7,717,890 (148)

A retrospective cohort study on the association between poor sleep quality in junior high school students and high hemoglobin A1c level in early adults with higher body mass index values

BMC Endocrine Disorders, 2022
Background Few epidemiological studies have been performed to clarify the association between glucose metabolism disorders in early adults (20 years old) and physiological and environmental factors, including body mass index (BMI) in junior high school ...
Tomoko Kasahara, Hiromasa Tsujiguchi, Yumie Takeshita, Akinori Hara, Keita Suzuki, Nobuhiko Narukawa, Koichiro Hayashi, Masateru Miyagi, Atsushi Asai, Yohei Yamada, Haruki Nakamura, Fumihiko Suzuki, Kim-Oanh Pham, Toshio Hamagishi, Masaharu Nakamura, Aki Shibata, Yukari Shimizu, Thao Thi Thu Nguyen, Sakae Miyagi, Yasuhiro Kambayashi, Takayuki Kannon, Atsushi Tajima, Hirohito Tsuboi, Tadashi Konoshita, Toshinari Takamura, Hiroyuki Nakamura   +25 more
doaj   +1 more source

CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587

Journal of Translational Medicine, 2022
Glioblastoma (GBM) is the most common and aggressive malignant primary brain tumor. E3 ligases play important functions in glioma pathogenesis. CRISPR system offers a powerful platform for genome manipulation, while the screen of E3 ligases in GBM still ...
Kun Lin, Shang-Hang Shen, Feng Lu, Pengfeng Zheng, Shizhong Wu, Jingwei Liao, Xiaohang Jiang, Guangming Zeng, De Wei   +8 more
doaj   +1 more source

Semiquantitative microscopic pore characterizations of the metamorphic rock reservoir in the central paleo-uplift belt, Songliao Basin

Scientific Reports, 2022
Currently, metamorphic rock is a common target for natural gas exploration, and reservoirs are the key factors restricting natural gas exploration and development in metamorphic rocks.
Zhouqiang Zeng, Xuanlong Shan, Guoli Hao, Wentong He, Changqing Zheng, Jian Yi, Jiannan Guo   +6 more
doaj   +1 more source

Comprehensive analysis of the expression and significance of CXCLs in human diffuse large B-cell lymphoma

Scientific Reports, 2022
CXCL chemokines (CXCLs) are small cytokines or signal proteins secreted by cells that have been proven to be linked to the occurrence and development of many kinds of cancer. However, the expression and diagnostic and prognostic value of CXCLs in diffuse
Xiaonan Zhou, Shizhu Guo, Yonghong Shi
doaj   +1 more source

A comparative analysis of single cell small RNA sequencing data reveals heterogeneous isomiR expression and regulation

Scientific Reports, 2022
MicroRNAs (miRNAs) are non-coding small RNAs which play a critical role in the regulation of gene expression in cells. It is known that miRNAs are often expressed as multiple isoforms, called isomiRs, which may have alternative regulatory functions ...
Christopher Michael Smith, Gyorgy Hutvagner   +1 more
doaj   +1 more source

The impacts of faecal subsampling on microbial compositional profiling

BMC Research Notes, 2022
Objective Despite the move to at-home, small-volume collection kits to facilitate large population-based studies of faecal microbial compositional profiling, there remains limited reporting on potential impacts of faecal subsampling approaches on ...
Amanda J. Cox, Lily Hughes, Tiffanie M. Nelson, Kyle M. Hatton-Jones, Rebecca Ramsey, Allan W. Cripps, Nicholas P. West   +6 more
doaj   +1 more source

Efficacy and safety of Androgen Deprivation Therapy (ADT) combined with modified docetaxel chemotherapy versus ADT combined with standard docetaxel chemotherapy in patients with metastatic castration-resistant prostate cancer: study protocol for a multicentre prospective randomized controlled trial

BMC Cancer, 2022
Background Androgen deprivation therapy (ADT) combined with docetaxel chemotherapy is the standard treatment for metastatic castration-resistant prostate cancer (mCRPC) patients.
Xiangwei Yang, Hong Chen, Duanya Xu, Xianju Chen, Yamei Li, Jun Tian, Dongwen Wang, Jun Pang   +7 more
doaj   +1 more source

The genetic landscape of pancreatic head ductal adenocarcinoma in China and prognosis stratification

BMC Cancer, 2022
Background Pancreatic ductal adenocarcinoma (PDAC) is the major subtype of pancreatic cancer and head PDACs show distinct characteristics from body/tail PDACs. With limited studies based on Asian population, the mutational landscape of Asian PDAC remains
Yefan Yang, Ying Ding, Yuxi Gong, Sha Zhao, Mingna Li, Xiao Li, Guoxin Song, Boya Zhai, Jin Liu, Yang Shao, Liuqing Zhu, Jiaohui Pang, Yutong Ma, Qiuxiang Ou, Xue Wu, Zhihong Zhang   +15 more
doaj   +1 more source

Audit identified modifiable factors in Hospital Care of Newborns in low-middle income countries: a scoping review

BMC Pediatrics, 2022
Background Audit of facility-based care provided to small and sick newborns is a quality improvement initiative that helps to identify the modifiable gaps in newborn care (BMC Pregnancy Childbirth 14: 280, 2014).
Muthoni Ogola, Emily Mbaire Njuguna, Jalemba Aluvaala, Mike English, Grace Irimu   +4 more
doaj   +1 more source

Historical reconstruction of the population dynamics of southern right whales in the southwestern Atlantic Ocean

Scientific Reports, 2022
Understanding the recovery of whale populations is critical for developing population-management and conservation strategies. The southern right whale (SRW) Eubalena australis was one of the baleen whale species that has experienced centuries of ...
M. A. Romero, M. A. Coscarella, G. D. Adams, J. C. Pedraza, R. A. González, E. A. Crespo   +5 more
doaj   +1 more source