Shape Memory Alloy (SMA) Actuators: The Role of Material, Form, and Scaling Effects
Advances in Materials, 2023 Shape memory alloys (SMAs) are smart materials that are widely used to create intelligent devices because of their high energy density, actuation strain, and biocompatibility characteristics.
Min‐Soo Kim +6 more
semanticscholar +1 more source
Cureus, 2023 Spinal Muscular Atrophy (SMA) is a genetic disease that causes weakness and wasting in the voluntary muscles of infants and children. SMA has been the leading inherited cause of infant death.
Tolu Ogbonmide +7 more
semanticscholar +1 more source
Impaired prenatal motor axon development necessitates early therapeutic intervention in severe SMA
Science Translational Medicine, 2021 Fetal delays of SMA motor axon radial growth coupled with rapid postnatal degeneration require very early delivery of SMN induction treatments. The sooner, the better Gene therapy approaches hold promise for the treatment of spinal muscular atrophy (SMA).
L. Kong +22 more
semanticscholar +1 more source
Hysteretic response and failure behavior of an SMA cable‐based self‐centering brace
Structural Control & Health Monitoring, 2021 This study explores the experimental response and failure behavior of an SMA cable brace. The kernel of the developed SMA brace consists of four SMA cables with a diameter of 8 mm.
F. Shi, Yun Zhou, O. Ozbulut, F. Ren
semanticscholar +1 more source
α-Smooth muscle actin expression in cancerassociated fibroblasts in canine epithelial tumors [PDF]
, 2017 Tumor tissues contain not only cancer cells but also other cell types including, fibroblasts, immune cells, and endothelial cells, which interact with cancer cells.
Hoshino, Yuki +3 more
core +1 more source
Behavior and application of self-centering dampers equipped with buckling-restrained SMA bars
Smart materials and structures (Print), 2020 This study proposes a new type of self-centering damper equipped with novel buckling-restrained superelastic shape memory alloy (SMA) bars. The new solution aims to address some critical issues related to degradation and loss of superelasticity observed ...
C. Qiu +4 more
semanticscholar +1 more source
Abnormal motoneuron migration, differentiation, and axon outgrowth in spinal muscular atrophy [PDF]
, 2008 The role of heterotopic (migratory) motoneurons (HMN) in the pathogenesis of spinal muscular atrophy (SMA) is still controversial. We examined the occurrence and amount of HMN in spinal cord tissue from eight children with SMA (six with SMA-I and two ...
Barišić, Nina +10 more
core +1 more source
Label-free proteomics identifies Calreticulin and GRP75/Mortalin as peripherally accessible protein biomarkers for spinal muscular atrophy [PDF]
, 2013 BACKGROUND: Spinal muscular atrophy (SMA) is a neuromuscular disease resulting from mutations in the survival motor neuron 1 (SMN1) gene. Recent breakthroughs in preclinical research have highlighted several potential novel therapies for SMA, increasing ...
Gillingwater, T. H. +4 more
core +3 more sources
Journal of Medicinal Chemistry, 2018 SMA is an inherited disease that leads to loss of motor function and ambulation and a reduced life expectancy. We have been working to develop orally administrated, systemically distributed small molecules to increase levels of functional SMN protein ...
H. Ratni +27 more
semanticscholar +1 more source
Natural history of Type 2 and 3 spinal muscular atrophy: 2‐year NatHis‐SMA study
Annals of Clinical and Translational Neurology, 2020 To characterize the natural history of spinal muscular atrophy (SMA) over 24 months using innovative measures such as wearable devices, and to provide evidence for the sensitivity of these measures to determine their suitability as endpoints in clinical ...
M. Annoussamy +21 more
semanticscholar +1 more source