Results 221 to 230 of about 8,011,267 (345)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Establishing a Research Agenda for Physiotherapy in Portugal: A Delphi Study. [PDF]

open access: yesPhysiother Res Int
Silva I   +7 more
europepmc   +1 more source

Deletion analysis of Bulgarian SMA families

open access: gold, 1998
Albena Jordanova   +4 more
openalex   +1 more source

Fabrication and characterization of SMA hybrid composites [PDF]

open access: green, 2001
Travis L. Turner   +2 more
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A Minimal Annotation Pipeline for Deep Learning Segmentation of Skeletal Muscles. [PDF]

open access: yesNMR Biomed
Baudin PY   +7 more
europepmc   +1 more source

A millimeter-Sized Robot Using SMA and Its Control

open access: hybrid, 1995
Katsutoshi Kuribayashi, Seiji Shimizu
openalex   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

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