Results 231 to 240 of about 8,994,995 (387)

Assessing the Quantitative Performance of Atmospheric Solids Analysis Probe-Mass Spectrometry. [PDF]

Rapid Commun Mass Spectrom
Henderson A, Rankin-Turner S, Reynolds JC, Turner MA, Sage A, Douce D, Thevis M, Heaney LM.   +7 more
europepmc   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Social cohesion, trust, and utilisation of maternal health services among refugee and host community women in Bangladesh and Kenya. [PDF]

Disasters
Lee H, Rego R, Fiseha N, Barman AK, Sharif N, Wachira P, Kolars J, Waljee A, Rakqib R, Islam MS, Abubakar A.   +10 more
europepmc   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Evaluation of a QI Module for Psychiatry Residents. [PDF]

Clin Teach
Vasudev K, Reiss JP.
europepmc   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Involving Patients Throughout Sensitive Simulation. [PDF]

Clin Teach
Tremblay ML, Fournier C.
europepmc   +1 more source

Complete sequencing of the SMN2 gene in SMA patients detects SMN gene deletion junctions and variants in SMN2 that modify the SMA phenotype

Human Genetics, 2019
C. Ruhno, V. McGovern, Matthew R. Avenarius, P. Snyder, T. Prior, F. Nery, Abdurrahman W. Muhtaseb, J. Roggenbuck, J. Kissel, Valeria A. Sansone, J. Siranosian, A. Johnstone, Pann H. Nwe, Ren Zhang, K. Swoboda, A. Burghes   +15 more
semanticscholar   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Health Promotion Opportunities for Lesbian, Gay and Bisexual People: Using Data From the New Zealand Health Survey. [PDF]

Health Promot J Austr
Adams J, Jankhotkaew J, Ellis SJ, Neville S.   +3 more
europepmc   +1 more source