Label-free proteomics identifies Calreticulin and GRP75/Mortalin as peripherally accessible protein biomarkers for spinal muscular atrophy [PDF]
, 2013 BACKGROUND: Spinal muscular atrophy (SMA) is a neuromuscular disease resulting from mutations in the survival motor neuron 1 (SMN1) gene. Recent breakthroughs in preclinical research have highlighted several potential novel therapies for SMA, increasing ...
Gillingwater, T. H. +4 more
core +3 more sources
Трансплантология (Москва), 2020 We present an uncommon case of liver graft dysfunction caused by seronegative hepatitis C-related fibrosing cholestatic hepatitis after cadaver liver transplantation for unresectable liver metastases of neuroendocrine small intestine cancer followed by ...
S. E. Voskanyan +9 more
doaj +1 more source
Behavior and application of self-centering dampers equipped with buckling-restrained SMA bars
Smart materials and structures (Print), 2020 This study proposes a new type of self-centering damper equipped with novel buckling-restrained superelastic shape memory alloy (SMA) bars. The new solution aims to address some critical issues related to degradation and loss of superelasticity observed ...
C. Qiu +4 more
semanticscholar +1 more source
eXPRESS Polymer Letters, 2018 Poly(trimethylene 2,5-furanoate) (PTF) nanocomposites reinforced with few layer graphene (FLG) were prepared through in situ polymerization. The method in question allows obtaining well-dispersed nanoplatelets in the whole volume of PTF matrix.
S. Paszkiewicz +8 more
doaj +1 more source
Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment.
Journal of Clinical Investigation, 2019 BACKGROUNDSpinal muscular atrophy (SMA) is caused by deficient expression of survival motor neuron (SMN) protein. New SMN-enhancing therapeutics are associated with variable clinical benefits.
Daniel M. Ramos +21 more
semanticscholar +1 more source
Electrocardiographic (ECG) criteria for determining left ventricular mass in young healthy men; data from the LARGE Heart study [PDF]
, 2009 Background: Doubts remain over the use of the ECG in identifying those with increased left ventricular (LV) mass. This is especially so in young individuals, despite their high prevalence of ECG criteria for LV hypertrophy.
Montgomery, HE +5 more
core +2 more sources
Bilateral segmentectomies using virtual-assisted lung mapping (VAL-MAP) for metastatic lung tumors
Surgical Case Reports, 2017 Background Virtual-assisted lung mapping (VAL-MAP) has been used not only in wedge resection but also in segmentectomy for hardly palpable lung nodules.
Keita Nakao +3 more
doaj +1 more source
Restoration of SMN in Schwann cells reverses myelination defects and improves neuromuscular function in spinal muscular atrophy [PDF]
, 2016 Spinal muscular atrophy (SMA) is a neuromuscular disease caused by low levels of SMN protein, primarily affecting lower motor neurons. Recent evidence from SMA and related conditions suggests that glial cells can influence disease severity.
Brophy, Peter J. +9 more
core +3 more sources
Communications in Development and Assembling of Textile Products, 2023 Developments in textile and fiber engineering have allowed the development of functional clothing such as protective wear, sportswear, and medical clothing.
Dominique Almendariz +2 more
doaj
Treatment algorithm for infants diagnosed with spinal muscular atrophy through newborn screening [PDF]
, 2018 Spinal muscular atrophy (SMA) is an autosomal recessive disease characterized by the degeneration of alpha motor neurons in the spinal cord, leading to muscular atrophy.
Connolly, Anne +14 more
core +2 more sources