Results 31 to 40 of about 8,011,267 (345)

Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment.

Journal of Clinical Investigation, 2019
BACKGROUNDSpinal muscular atrophy (SMA) is caused by deficient expression of survival motor neuron (SMN) protein. New SMN-enhancing therapeutics are associated with variable clinical benefits.
Daniel M. Ramos, C. d’Ydewalle, V. Gabbeta, A. Dakka, S. Klein, Daniel A. Norris, J. Matson, Shannon J. Taylor, P. Zaworski, Thomas W. Prior, Pamela J. Snyder, D. Valdivia, Christine L. Hatem, Ian G. Waters, N. Gupte, Kathryn J. Swoboda, F. Rigo, C. F. Bennett, Nikolai Naryshkin, S. Paushkin, Thomas O Crawford, Charlotte J. Sumner   +21 more
semanticscholar   +1 more source

Comparison of the Complete Eragrostis pilosa Chloroplast Genome with Its Relatives in Eragrostideae (Chloridoideae; Poaceae)

Plants, 2019
Eragrostis of the tribe Eragrostideae is a taxonomically complex genus, because of its polyploid nature and the presence of similar morphological characters among its species.
Yamuna Somaratne, De-Long Guan, Nibras Najm Abbood, Liang Zhao, Wen-Qiang Wang, Sheng-Quan Xu   +5 more
doaj   +1 more source

Insect Target Classes Discerned from Entomological Radar Data

Remote Sensing, 2020
Entomological radars employing the ‘ZLC’ (zenith-pointing linear-polarized narrow-angle conical scan) configuration detect individual insects flying overhead and can retrieve information about a target’s trajectory (its direction and ...
Zhenhua Hao, V. Alistair Drake, John R. Taylor, Eric Warrant   +3 more
doaj   +1 more source

A 2D semi-analytical analysis of the time-dependent settlement of a shallow foundation placed near the soil slope [PDF]

Analytical and Numerical Methods in Mining Engineering, 2022
To assess the safety of the foundation, the ultimate bearing capacity, as well as the settlement of the footing, should be studied. The bearing capacity of a footing built near the slope has been widely investigated.
هادی حقگویی, علی رضا کارگر, محمد حسین خسروی, مهدی امینی   +3 more
doaj   +1 more source

Esvaziamento gástrico e jejunal proximal em ratos submetidos ou não à gastrectomia parcial com reconstrução do trânsito intestinal em Y de Roux ou a Billroth II Gastric and proximal jejunum emptying in rats submitted or not to partial gastrectomy with Roux-en Y or Billroth II reconstruction

Acta Cirúrgica Brasileira, 1997
Estudou-se os efeitos da reconstrução gastrojejunal em Y de ROUX (YR) ou a BILLROTH II (BII) no esvaziamento gástrico (EG) e jejunal proximal de líquido nutriente.
Flavio José Garani, Neil Ferreira Novo, Yara Juliano, Djalma José Fagundes   +3 more
doaj   +1 more source

Innovative Remote Sensing Methodologies for Kenyan Land Tenure Mapping

Remote Sensing, 2020
There exists a demand for effective land administration systems that can support the protection of unrecorded land rights, thereby assisting to reduce poverty and support national development—in alignment with target 1.4 of UN Sustainable ...
Mila Koeva, Claudia Stöcker, Sophie Crommelinck, Serene Ho, Malumbo Chipofya, Jan Sahib, Rohan Bennett, Jaap Zevenbergen, George Vosselman, Christiaan Lemmen, Joep Crompvoets, Ine Buntinx, Gordon Wayumba, Robert Wayumba, Peter Ochieng Odwe, George Ted Osewe, Beatrice Chika, Valerie Pattyn   +17 more
doaj   +1 more source

NFL is a marker of treatment response in children with SMA treated with nusinersen

Journal of Neurology, 2019
BackgroundRecently, the anti-sense oligonucleotide drug nusinersen was approved for spinal muscular atrophy (SMA) and our aim was to find a response marker for this treatment.MethodsTwelve children with SMA type 1 and two copies of the SMN2 gene were ...
B. Olsson, L. Alberg, N. Cullen, E. Michael, L. Wahlgren, A. Kroksmark, K. Rostásy, K. Blennow, H. Zetterberg, M. Tulinius   +9 more
semanticscholar   +1 more source

Investigating the Norse Harbour of Igaliku (Southern Greenland) Using an Integrated System of Side-Scan Sonar and High-Resolution Reflection Seismics

Remote Sensing, 2019
This study presents the results of a marine geophysical survey performed in the Igaliku fjord in southern Greenland in order to understand the harbour setting of the former Norse settlement Garðar (modern Igaliku).
Dennis Wilken, Tina Wunderlich, Peter Feldens, Joris Coolen, John Preston, Natascha Mehler   +5 more
doaj   +1 more source

One Year of Newborn Screening for SMA – Results of a German Pilot Project

Journal of Neuromuscular Diseases, 2019
Objective: Spinal muscular atrophy (SMA) is the most common neurodegenerative disease in childhood. The study was conducted to assess the impact of early detection of SMA by newborn screening (NBS) on the clinical course of the disease.
K. Vill, H. Kölbel, O. Schwartz, A. Blaschek, B. Olgemöller, E. Harms, S. Burggraf, W. Röschinger, J. Durner, D. Gläser, U. Nennstiel, B. Wirth, U. Schara, Beate Jensen, M. Becker, K. Hohenfellner, W. Müller-Felber   +16 more
semanticscholar   +1 more source

Vegetation Response to the 2012–2014 California Drought from GPS and Optical Measurements

Remote Sensing, 2018
We compare microwave GPS and optical-based remote sensing observations of the vegetation response to a recent drought in California, USA. The microwave data are based on reflected GPS signals that were collected by a geodetic network.
Eric E. Small, Carolyn J. Roesler, Kristine M. Larson   +2 more
doaj   +1 more source