Results 41 to 50 of about 9,214,882 (387)

The L723 low mass star forming protostellar system: resolving a double core

, 2008
We present 1.35 mm SMA observations around the low-mass Class 0 source IRAS 19156+1906, at the the center of the L723 dark cloud. We detected emission from dust as well as emission from H2CO, DCN and CN, which arise from two cores, SMA 1 and SMA 2 ...
Anglada, Anglada, Carrasco-González, Chen, Codella, Danby, Draine, Estalella, Furuya, Girart, Girart, Hirano, Hogerheijde, J. M. Girart, Launhardt, Lee, Ossenkopf, Palacios, R. Estalella, R. Rao, Rodríguez, Shirley   +21 more
core   +1 more source

Submillimeter Array multiline observations of the massive star-forming region IRAS 18089-1732 [PDF]

, 2004
Submillimeter Array (SMA) observations of the high-mass star-forming region IRAS 18089-1732 in the 1 mm and 850 $\mu$m band with 1 GHz bandwidth reveal a wealth of information.
Beuther, H., Ho, P. T. P., Hunter, T. R., Lim, J., Liu, S. -Y., Ohashi, N., Sollins, P., Sridharan, T. K., Su, Y. N., Zhang, Q., Zhao, J. -H.   +10 more
core   +1 more source

One Year of Newborn Screening for SMA – Results of a German Pilot Project

Journal of Neuromuscular Diseases, 2019
Objective: Spinal muscular atrophy (SMA) is the most common neurodegenerative disease in childhood. The study was conducted to assess the impact of early detection of SMA by newborn screening (NBS) on the clinical course of the disease.
K. Vill, H. Kölbel, O. Schwartz, A. Blaschek, B. Olgemöller, E. Harms, S. Burggraf, W. Röschinger, J. Durner, D. Gläser, U. Nennstiel, B. Wirth, U. Schara, Beate Jensen, M. Becker, K. Hohenfellner, W. Müller-Felber   +16 more
semanticscholar   +1 more source

Cheminformatics-based identification of phosphorylated RET tyrosine kinase inhibitors for human cancer

Frontiers in Chemistry
BackgroundRearranged during transfection (RET), an oncogenic protein, is associated with various cancers, including non-small-cell lung cancer (NSCLC), papillary thyroid cancer (PTC), pancreatic cancer, medullary thyroid cancer (MTC), breast cancer, and ...
Md. Enamul Kabir Talukder, Md. Enamul Kabir Talukder, Md. Aktaruzzaman, Md. Aktaruzzaman, Noimul Hasan Siddiquee, Noimul Hasan Siddiquee, Sabrina Islam, Tanveer A. Wani, Hamad M. Alkahtani, Seema Zargar, Md. Obayed Raihan, Md. Mashiar Rahman, Sushil Pokhrel, Foysal Ahammad   +13 more
doaj   +1 more source

Enhanced oral bioavailability of cannabidiol by flexible zein nanoparticles: in vitro and pharmacokinetic studies

Frontiers in Nutrition
IntroductionCannabidiol (CBD) has a variety of pharmacological effects including antiepileptic, antispasmodic, anxiolytic and anti-inflammatory among other pharmacological effects.
YingLan Nie, Yan Kong, Juan Peng, Jian Sun, Bin Fan   +4 more
doaj   +1 more source

Fluorescent markers in microscopy: photophysical characteristics and applications in cell biology

Acta Biologica Slovenica, 2016
In the fluorescence microscopy of biological specimens the structures in cells and tissues usually need to be labelled with various fluorescent markers.
Urban Bogataj, Jasna Štrus, Nada Žnidaršič, Marko Kreft   +3 more
doaj   +1 more source

An Integrated Safety Analysis of Infants and Children with Symptomatic Spinal Muscular Atrophy (SMA) Treated with Nusinersen in Seven Clinical Trials

CNS Drugs, 2019
Treatment with nusinersen has demonstrated significant and clinically meaningful benefits in clinical trials in infants and children with spinal muscular atrophy (SMA).
B. Darras, M. Farrar, E. Mercuri, R. Finkel, R. Foster, S. Hughes, I. Bhan, W. Farwell, S. Gheuens   +8 more
semanticscholar   +1 more source

Prospective and longitudinal natural history study of patients with Type 2 and 3 spinal muscular atrophy: Baseline data NatHis-SMA study

PLoS ONE, 2018
Spinal muscular atrophy (SMA) is a monogenic disorder caused by loss of function mutations in the survival motor neuron 1 gene, which results in a broad range of disease severity, from neonatal to adult onset.
A. Chabanon, A. Seferian, A. Daron, Y. Péréon, C. Cances, C. Vuillerot, L. De Waele, J. Cuisset, V. Laugel, U. Schara, T. Gidaro, S. Gilabert, J. Hogrel, P. Baudin, P. Carlier, E. Fournier, L. Lowes, N. Hellbach, T. Seabrook, E. Toledano, M. Annoussamy, L. Servais   +21 more
semanticscholar   +1 more source

The unpredictably eruptive dynamics of spruce budworm populations in eastern Canada

Population Ecology, EarlyView.
We examine historical population data for spruce budworm from several locations through the period 1930–1997, and use density‐dependent recruitment curves to test whether the pattern of population growth over time is more consistent with Royama's (1984; Ecological Monographs 54:429–462) linear R(t) model of harmonic oscillation at Green River New ...
Barry J. Cooke, Jacques Régnière
wiley   +1 more source

A three-dimensional lattice-free agent-based model of intracellular ice formation and propagation and intercellular mechanics in liver tissues

Royal Society Open Science
A successful cryopreservation of tissues and organs is crucial for medical procedures and drug development acceleration. However, there are only a few instances of successful tissue cryopreservation.
Fatemeh Amiri, James D. Benson
doaj   +1 more source