Results 81 to 90 of about 9,380,370 (380)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A manipulator arm for zero-g simulations [PDF]

, 1975
A 12-ft counterbalanced Slave Manipulator Arm (SMA) was designed and fabricated to be used for resolving the questions of operational applications, capabilities, and limitations for such remote manned systems as the Payload Deployment and Retrieval ...
Brodie, S. B., Grant, C., Lazar, J. J.
core   +1 more source

WDR79/TCAB1 plays a conserved role in the control of locomotion and ameliorates phenotypic defects in SMA models [PDF]

, 2017
SMN (Survival Motor Neuron) deficiency is the predominant cause of spinal muscular atrophy (SMA), a severe neurodegenerative disorder that can lead to progressive paralysis and death.
Bavasso, Francesca, Cacchione, Stefano, DI GIORGIO, MARIA LAURA, Esposito, Alessandro, Feiguin, Fabian, Gallotta, Ivan, Maccallini, Paolo, Mccabe, Brian D., Micheli, Emanuela, Raffa, GRAZIA DANIELA, Schiavi, Elia Di, Verni', Fiammetta   +11 more
core   +1 more source

MENINGKATKAN HASIL BELAJAR SISWA PADA MATERI UKURAN PEMUSATAN DATA DENGAN MENGGUNAKAN VIDEO DI KELAS XI SMA NEGERI 1 UJAN MAS [PDF]

, 2022
Senja Purnama Sari
openalex   +1 more source

Neurochemical markers in CSF of adolescent and adult SMA patients undergoing nusinersen treatment

Therapeutic Advances in Neurological Disorders, 2019
Background: There is limited information on neurochemical markers being used to support and monitor the affection of motoneurons in patients with spinal muscular atrophy (SMA).
C. Wurster, R. Günther, P. Steinacker, J. Dreyhaupt, K. Wollinsky, Z. Uzelac, S. Witzel, T. Kocak, B. Winter, J. Koch, P. Lingor, S. Petri, A. Ludolph, A. Hermann, M. Otto   +14 more
semanticscholar   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

A shape memory alloy adaptive tuned vibration absorber: design and implementation

, 2005
In this paper a tuned vibration absorber (TVA) is realized using shape memory alloy (SMA) elements. The elastic modulus of SMA changes with temperature and this effect is exploited to develop a continuously tunable device.A TVA with beam elements is ...
Brennan, M.J., Mace, B.R., Rustighi, E.
core   +1 more source

Discovery of Small Molecule Splicing Modulators of Survival Motor Neuron-2 (SMN2) for the Treatment of Spinal Muscular Atrophy (SMA).

Journal of Medicinal Chemistry, 2018
Spinal muscular atrophy (SMA), a rare neuromuscular disorder, is the leading genetic cause of death in infants and toddlers. SMA is caused by the deletion or a loss of function mutation of the survival motor neuron 1 (SMN1) gene.
Atwood K Cheung, Brian Hurley, Ryan Kerrigan, Lei Shu, D. Chin, Yiping Shen, Gary O'Brien, M. Sung, Ying Hou, Jake Axford, Emma Cody, Robert Sun, A. Fazal, Cary Fridrich, C. Sánchez, R. Tomlinson, Monish Jain, Lin Deng, K. Hoffmaster, Cheng Song, Mailin Van Hoosear, Y. Shin, Rebecca Servais, C. Towler, M. Hild, D. Curtis, W. Dietrich, L. Hamann, K. Briner, Karen S. Chen, D. Kobayashi, Rajeev Sivasankaran, N. Dales   +32 more
semanticscholar   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Central free-free-dominated 880 $\micron$ emission in II Zw 40

, 2011
The central star-forming region in a blue compact dwarf galaxy, II Zw 40, was observed in the 340 GHz ($880 \micron$) band at $\sim 5$ arcsec (250 pc) resolution with the Submillimetre Array (SMA).
Arbutina, Beck, Beck, Becker, Bianchi, Buat, Buckalew, Calzetti, Cannon, Cannon, Condon, Condon, Condon, de Jong, Deeg, Dopita, Draine, Draine, Dumas, Dunne, Elmegreen, Engelbracht, Gall, Galliano, Garrett, Gomez, Grassi, Gruppioni, Helou, Helou, Helou, Hirashita, Hirashita, Hirashita, Hirashita, Hirashita, Hiroyuki Hirashita, Ho, Hopkins, Hughes, Hunt, Hunt, Ibar, Inoue, Jaffe, James, Johnson, Kennicutt, Klein, Kobulnicky, Kozasa, Lacki, Lada, Leitch-Devlin, Leitherer, Lodders, Matsuura, Michałowski, Murphy, Murphy, Murphy, Nagata, Niklas, Nozawa, Nozawa, Nozawa, Osterbrock, Price, Rho, Sargent, Schaerer, Seymour, Spitzer, Takeuchi, Takeuchi, Thuan, Todini, Turner, Ulvestad, Vacca, Vader, Valiante, van Zee, Vanzi, Vlahakis, Völk, Westera, Wilson, Wu, Xu   +89 more
core   +1 more source