Results 81 to 90 of about 8,011,267 (345)
New Directions for SMA Therapy [PDF]
Journal of Clinical Medicine, 2018 Spinal muscular atrophy (SMA) is a severe disorder of motor neurons and the most frequent genetic cause of mortality in childhood, due to respiratory complications. The disease occurs due to mutations in the survival motor neuron 1 (SMN1) gene that leads to a reduction in the SMN protein, causing degeneration of lower motor neurons, muscle weakness and
openaire +3 more sources
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
FEBS Letters, EarlyView.In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti +3 more
wiley +1 more source
Remote Sensing, 2018 Mapping plant communities is a difficult and time consuming endeavor. Methods relying on field surveys deliver high quality data but are usually limited to relatively small areas.
Adriana Marcinkowska-Ochtyra +4 more
doaj +1 more source
PENGARUH MINAT DAN KEBIASAAN BELAJAR TERHADAP HASIL BELAJAR BIOLOGI SISWA SMA SE-KOTA STABAT
JURNAL BIOLOKUS, 2018 Penelitian ini bertujuan untuk mengetahui pengaruh minat siswa dan kesiapan belajar terhadap hasil belajar biologi siswa SMA di Kota Stabat. Penelitian ini dilakukan di SMA Negeri Se-Kota Stabat pada tahun 2015.
Muhammad Hasyim Ansari Berutu +1 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Journal of Rehabilitation Medicine, 2019 Objective: To identify the anatomical landmarks of tibial motor nerve branches to the gastrocnemii, soleus and tibialis posterior muscles for selective motor nerve blocks in the management of spastic equinovarus foot.
Alessandro Picelli +8 more
doaj +1 more source
Mìžnarodnij Endokrinologìčnij Žurnal, 2012 In the blood taken from 90 patients with inactive pituitary adenoma the high level of apoptosis markers р53, Bcl-2 and TNF-α is found. Cabergoline administered in high doses restored apoptosis markers in blood of patients more effectively and earlier ...
S.I. Ismailov +2 more
doaj +1 more source
Patient Reported Impact of Symptoms in Spinal Muscular Atrophy (PRISM-SMA)
Neurology, 2018 Objective To determine the frequency and relative importance of symptoms experienced by adults with spinal muscular atrophy (SMA) and to identify factors that are associated with a higher burden of disease in this population. Methods We conducted a cross-
P. Mongiovi +8 more
semanticscholar +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source