Results 131 to 140 of about 435,801 (297)

Stage‐Adaptive Janus Microneedle System for Redox‐Immune Regulation and Mitochondrial Protection in Infected Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
ABSTRACT Infected diabetic wounds are sustained by a vicious cycle of hyperglycemia‐driven bacterial infection, persistent oxidative stress, and excessive inflammation, which collectively disrupt the ordered progression of tissue repair. Here, we engineered a stage‐adaptive Janus microneedle patch (MN‐FeSAC‐PPE) to enable a staged therapeutic process ...
Mengting Yin   +13 more
wiley   +1 more source

Development of Therapies for Spinal Muscular Atrophy Using Gene Therapy and Nanotechnology [PDF]

open access: yes, 2013
Spinal muscular atrophy (SMA) is a genetic disease which is characterized by muscle weakness and atrophy. The disease arises from mutations in the survival motor neuron 1 (SMN1) gene causing degeneration of spinal cord motor neurons.
Little, Daniel
core  

EFFECT OF COMPACTING PRESSURE ON MICROSTRUCTURE,PHYSICAL AND MECHANICAL PROPERTIES OF NiTi SMA

open access: yesAl-Qadisiyah Journal for Engineering Science, 2016
This study investigates the effect of different compacting pressures on microstructure ,physical and mechanical properties of NiTi shape memory alloys. The sample were prepared by powder metallurgy technique.
Noora Mohammed Gased   +2 more
doaj  

A Worm‐Inspired Origami Robot with Multimodal Locomotion for Adaptive Mobility in Complex Pipeline Environments

open access: yesAdvanced Science, EarlyView.
An origami worm‐inspired robot achieves multimodal locomotion in confined pipelines through mechatronic integration that embeds actuation, control, and communication within each origami module. Large, reversible configuration and dimensional changes enable 25 gaits synthesized by a unified framework across peristaltic, inchworm, and wheel‐rolling modes
Qiwei Zhang   +6 more
wiley   +1 more source

PENGARUH CARA BELAJAR DAN MOTIVASI BELAJAR TERHADAP KEMAMPUAN PEMECAHAN MASALAH SISWA KELAS XII SMA NEGERI 1 MAPPEDECENG [PDF]

open access: yes, 2018
Penelitian ini bertujuan untuk mengetahui (1) Mendapatkan informasi mengenai cara belajar yang dilakukan oleh siswa kelas XII SMA Negeri 1 Mappedeceng. (2) Mendapatkan informasi mengenai motivasi belajar yang dilakukan oleh siswa kelas XII SMA Negeri 1 ...
Makaraka, Awaluddin; SMA Negeri 1 Mappedeceng
core  

AVALIAÇÃO HIDROGEOLÓGICA DOS SISTEMAS AQUÍFEROS TUBARÃO E CRISTALINO DA PORÇÃO SUL DA UGRHI-05

open access: yesRevista Águas Subterrâneas, 2017
A região que abrange os municípios de Indaiatuba a Capivari apresenta crescente demanda por água subterrânea, decorrente dos crescimentos econômico e populacional.
Geraldo Hideo Oda   +4 more
doaj  

Hyperpolarization of [1‐13C]Ketoisocaproate‐d2 by Reversible Exchange with Parahydrogen Enables Profiling of Branched‐Chain‐Amino‐Acid Metabolism in Cellulo and in Vivo

open access: yesAdvanced Science, EarlyView.
We report the fast generation of biocompatible solutions of highly 13C‐hyperpolarized (≈11%) partially‐deuterated ketoisocaproate within <6 min using spin‐lock‐induced crossing and reversible exchange with parahydrogen (SLIC‐SABRE). This enables rapid detection of branched‐chain‐amino‐acid transferase 1 (BCAT1) protein expression and investigation of ...
Stefan Petersen   +18 more
wiley   +1 more source

Closed‐Loop Decoding and Intervention of Pain: A Novel BMI Strategy Integrating θ‐Band Detection and Mechano‐Electro‐Biological Coupled Hydrogels

open access: yesAdvanced Science, EarlyView.
A closed‐loop brain–machine interface with a PFAPT hydrogel electrode identifies prefrontal θ‐band as a neuropathic pain biomarker. The hydrogel enables stable 28 d ECoG recording and delivers θ‐triggered cortical stimulation, alleviating pain and affective behaviors in rats via bidirectional regulation of inflammation and central sensitization ...
Yun Ji   +17 more
wiley   +1 more source

A Portable Soft Robotic Glove with Fully Functional Thumb Assistance for Complex Dexterous Fine Motor Skills

open access: yesAdvanced Science, EarlyView.
A portable, sensorized, and controlled dexterous thumb‐enhanced glove helps stroke survivors swipe phones, twist caps, and perform other tasks. It is based on a powerful continuously, segmented origami dual chamber actuator to achieve active thumb CMC and MCP joint assistance and passively extend the IP joint.
Disheng Xie   +10 more
wiley   +1 more source

A Hydrogen Sulfide–Releasing Dynamic Hydrogel Modulates Coordinated Neurovascular, Immune, and Angiogenic Responses for Scar‐Suppressed Diabetic Wound Repair

open access: yesAdvanced Science, EarlyView.
ROS‐Responsive H2S Hydrogel (HAPPF) Coordinated Regeneration for High‐Quality Diabetic Wound Repair.A self‐regulating dynamic hydrogel is developed to deliver a fluorogenic H2S donor in response to excessive ROS. Released H2S acts as a master regulator to resolve chronic inflammation (M2 polarization), restore VEGF‐driven angiogenesis, and rebalance ...
Xuyang Ning   +7 more
wiley   +1 more source

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