Results 201 to 210 of about 1,117,883 (324)

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

Hybrid open and endovascular retrograde suction thrombectomy and stenting for acute proximal superior mesenteric artery thrombosis. [PDF]

J Vasc Surg Cases Innov Tech
Kessler JJ, Nelms JK, Benjamin ME, Neschis DG.   +3 more
europepmc   +1 more source

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source

Disparities in Spinal Muscular Atrophy-Related Mortality in the United States, 2018-2023. [PDF]

NeuroSci
Al-Salahat A, Sharma R.
europepmc   +1 more source

Spatial Profiling Reveals Distinct Molecular and Immune Evolution of Mouse Lung Adenocarcinoma Precancers with or Without Carcinogen Exposure

Advanced Science, EarlyView.
Tumor evolution in lung adenocarcinoma is shaped by genetic alterations and spatial immune dynamics. By integrating whole‐exome sequencing, imaging mass cytometry, and spatial transcriptomics across two mouse models, this study reveals how mutational burden, immune infiltration, and cell–state interactions evolve during early and late carcinogenesis ...
Bo Zhu, Muhammad Aminu, Pingjun Chen, Jian‐Rong Li, Chuanpeng Dong, Chenyang Li, Yanhua Tian, Shao‐Wei Lu, Hong Chen, Chenxi Ma, Xin Hu, Jie Ye, Andrew Y. Liu, Beibei Huang, Frank R. Rojas, Parra Cuentas. Edwin Roger, Ou Shi, Monique B. Nilsson, Alissa Poteete, Khaja B. Khan, Wei Lu, Luisa M. Solis Soto, Junya Fujimoto, Cara Haymaker, Ignacio I. Wistuba, Zhubo Wei, Linghua Wang, Don L. Gibbons, Ken Chen, Alexandre Reuben, Jason M. Schenkel, John V. Heymach, Chao Cheng, Jia Wu, Jianjun Zhang   +34 more
wiley   +1 more source

Decreased Broca-left supplementary motor area connectivity underlying auditory verbal hallucination: A resting-state NIRS study. [PDF]

Transl Psychiatry
Huang Z, Ma Y, Wang J, Song Y, Zhang J, Ye Z, Ouyang D, Ke D, Cao, Dong W.   +9 more
europepmc   +1 more source

Bioabsorbable Endovascular Adhesive Tape (BEAT) for Improving Vascular Regeneration

Advanced Science, EarlyView.
A bioabsorbable endovascular adhesive tape (BEAT) platform based on a hierarchical polyelectrolyte complex is developed to enhance drug delivery in the DCB system. The coating enables rapid transfer to the vessel, provides short‐term mechanical support, and promotes both immediate transfer and long‐term retention of drugs at the lesion site.
Jiarong Wang, Jing Wang, Xinyi Li, Bo Yu, Yiduo Chen, Yirong Guo, Honglin Qian, Meng Hu, Haoyang Liu, Wenhui Liu, Han Xu, Kefeng Ren, M. Cristina L. Martins, Jian Ji   +13 more
wiley   +1 more source

A rare case of bronchial glomus tumour of uncertain malignant potential

Journal of Current Oncology and Medical Sciences
Introduction: Glomus tumours are typically benign pericytic mesenchymal neoplasms, occurring in the soft tissues of distal extremities, and rarely seen in deep soft tissues and visceral locations. Malignant glomus tumours are exceedingly uncommon.
Sharanya Sathish, Shanthi Velusamy, Divya Vijayanarasimha, Arjun S Kashyap, Sanjeev Kulkarni   +4 more
doaj  

Adult Survival in SMA Type 1: A 23-Year Journey With Home Ventilation and Multidisciplinary Support. [PDF]

Clin Case Rep
Camelo-Filho AE, Jovino RM, Tomaz BS, Nóbrega PR, Holanda MA.   +4 more
europepmc   +1 more source

PENGARUH KECERDASAN EMOSIONAL, LINGKUNGAN KELUARGA DAN LINGKUNGAN SEKOLAH TERHADAP HASIL BELAJAR SISWA PADA MATA PELAJARAN EKONOMI : Survey Pada Siswa Kelas XI IPS SMA Swasta Kota Bandung [PDF]

, 2013
Vidia Utami
openalex