Results 241 to 250 of about 1,350,741 (373)

Tubule‐Derived IFN‐α Promotes GSDMD‐Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation

Advanced Science, EarlyView.
Mao and colleagues uncover a STAT2/IRF9‐dependent signaling axis through which tubular epithelial cell (TEC)‐derived IFN‐α induces gasdermin D (GSDMD)‐mediated pyroptosis in macrophages. This TEC‐macrophage feedback loop amplifies renal inflammation and fibrosis, providing mechanistic insight into the progression of chronic kidney disease and revealing
Yiping Xu, Yating Wang, Siming Jiang, Yi Li, Guanglan Li, Yuchu Liu, Siyuan Li, Yiming Zhou, Qinghua Liu, Yi Zhou, Wei Chen, Hongyu Li, Haiping Mao   +12 more
wiley   +1 more source

10H-phenothiazine exerts beneficial effects in spinal muscular atrophy in vitro and in vivo models. [PDF]

Sci Rep
Rasà DM, Stanga S, Santonicola P, Mazzarella N, Camera A, Matino I, Zampi G, Boido M, Di Schiavi E, Vercelli A.   +9 more
europepmc   +1 more source

PENGEMBANGAN DAN VALIDASI VIDEO PEMBELAJARAN BERBASIS EKSPERIMEN HEMATOLOGI PADA Rattus novergicus DALAM MATERI SISTEM SIRKULASI DI SMA

, 2023
Veiren Wangkanusa, Emma Mauren Moko, Livana Dethris Rawung, Ferny M. Tumbel, Anatje Lihiang, Dino Rahardiyan   +5 more
openalex   +2 more sources

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Development and validation of a multi-slice CTA-based prediction model for poor outcomes in isolated superior mesenteric artery dissection. [PDF]

Front Surg
Zhang K, Hong H, Tang Z, Feng J, Wang Q, He B.   +5 more
europepmc   +1 more source

KAJIAN PENYELENGGARAAN PENDIDIKAN KARAKTER DI SMA DAN SMK

, 2018
Sudiyono Sudiyono
openalex   +2 more sources

Giant Small‐Molecule Donors With Controlled Backbone Planarity Afford High‐Performance and Photostable Organic Solar Cells

Advanced Science, EarlyView.
Efficient and photostable organic solar cells (OSCs) are developed using giant small‐molecule donors (GSMDs) with controlled backbone planarity. By tuning alkyl side chain orientation, anti‐configured GSMD improved crystallinity and charge transport, yielding PCE of 15.4% and superior stability (t80% > 1500 h).
Hyerin Jeon, Seunghoon Song, Jin‐Woo Lee, Yun‐Hi Kim, Bumjoon J. Kim   +4 more
wiley   +1 more source

A Case of Superior Mesenteric Artery Occlusion Caused by Portal Vein Stenting. [PDF]

Interv Radiol (Higashimatsuyama)
Takata K, Sakai T, Ueda M, Takeuchi K, Komiya H, Yoshikawa D, Kanai S, Wakabayashi T, Kitano A, Toyooka M, Tsujikawa T.   +10 more
europepmc   +1 more source

Superelastic SMA U-shaped dampers with self-centering functions

, 2018
Bin Wang, Songye Zhu
semanticscholar   +1 more source

Spatial Profiling Reveals Distinct Molecular and Immune Evolution of Mouse Lung Adenocarcinoma Precancers with or Without Carcinogen Exposure

Advanced Science, EarlyView.
Tumor evolution in lung adenocarcinoma is shaped by genetic alterations and spatial immune dynamics. By integrating whole‐exome sequencing, imaging mass cytometry, and spatial transcriptomics across two mouse models, this study reveals how mutational burden, immune infiltration, and cell–state interactions evolve during early and late carcinogenesis ...
Bo Zhu, Muhammad Aminu, Pingjun Chen, Jian‐Rong Li, Chuanpeng Dong, Chenyang Li, Yanhua Tian, Shao‐Wei Lu, Hong Chen, Chenxi Ma, Xin Hu, Jie Ye, Andrew Y. Liu, Beibei Huang, Frank R. Rojas, Parra Cuentas. Edwin Roger, Ou Shi, Monique B. Nilsson, Alissa Poteete, Khaja B. Khan, Wei Lu, Luisa M. Solis Soto, Junya Fujimoto, Cara Haymaker, Ignacio I. Wistuba, Zhubo Wei, Linghua Wang, Don L. Gibbons, Ken Chen, Alexandre Reuben, Jason M. Schenkel, John V. Heymach, Chao Cheng, Jia Wu, Jianjun Zhang   +34 more
wiley   +1 more source