Results 221 to 230 of about 8,260 (293)

Functional Data Strengthen Clinical Validation of PhenoScore Phenotype‐Guided AI for ANKRD11 Missense Variants

open access: yesClinical Genetics, EarlyView.
PhenoScore, an AI framework integrating facial recognition and clinical phenotype data, accurately identifies pathogenic ANKRD11 missense variants associated with KBG syndrome (AUC 0.95). Validated against functional data, PhenoScore outperforms REVEL and complements AlphaMissense, providing objective phenotypic evidence to reduce variants of uncertain
Evi Andriessen   +5 more
wiley   +1 more source

Biocultural Approaches in the Society for the Anthropology of Food and Nutrition: A Reflection on 50 Years

open access: yesCulture, Agriculture, Food and Environment, EarlyView.
ABSTRACT On the occasion of SAFN's 50th anniversary I reflect on the development of biocultural and human evolutionary approaches to human diet and nutrition. I maintain that SAFN and its predecessors the Committee (1974–1987) and then Council on Nutritional Anthropology (1987–2004) have modeled, fostered, and advanced biocultural work in anthropology ...
Andrea S. Wiley
wiley   +1 more source

Syntaxonomic Conspectus of the Vegetation of Catalonia and Andorra. I: Hygropilous Herbaceous Communities [PDF]

open access: yes, 2000
Carreras i Raurell, Jordi   +3 more
core  

Land Reforms in Cuba: First Empirical Assessment on Productivity Using Crop‐Level Panel Data

open access: yesEconomics of Transition and Institutional Change, EarlyView.
ABSTRACT Land reforms implemented in Cuba since 2008 have aimed to increase agricultural production by distributing state‐owned idle lands with land‐use rights. The reforms restricted farmers with the rights from cultivating perennial and capital‐intensive crops.
Yoshihiko Hashiguchi   +1 more
wiley   +1 more source

Free Tools—Not So “Free”? The Evolution, Risks and Costs of Fishery Stock Assessment Tools

open access: yesFish and Fisheries, EarlyView.
ABSTRACT In fisheries stock assessment, free software tools have proliferated in recent years. These tools provide standardised and, in many cases, well‐tested and efficient ways to conduct and support stock assessments, making cutting edge expertise globally accessible.
Natalie Anne Dowling   +6 more
wiley   +1 more source

Lock, relax, load, and shoot: a molecular perspective on Nedd4 regulation

open access: yesThe FEBS Journal, EarlyView.
Structural basis of inactive and active states of the Nedd4 HECT E3 ligase subfamily, following a ‘lock, relax, load, and shoot’ mechanism. In the locked, autoinhibited state, intramolecular domain interactions restrain the HECT domain. Relaxation releases these restraints, allowing loading of ubiquitin onto the catalytic cysteine, followed by the ...
Masa Janosev   +2 more
wiley   +1 more source

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