Results 161 to 170 of about 979,343 (349)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The regulators and the regulated: fisheries management, options and dynamics in Kenya's Lake Victoria fishery [PDF]

, 1997
The study divides the history of the fishery into five 'regulatory periods': the pre-colonial fishery (pre-1901), the colonial fishery (1901-1963), the post indipendence fishery (1963-1980), the Nile perch 'boom' years (1980-1989), and finally the ...
Geheb, K.
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Proposing Dimensions of an Agroecological Fishery: The Case of a Small-Scale Indigenous-Led Fishery Within Northwest Territories, Canada

Conservation
As fisheries face intersecting ecological and economic crises, small-scale fishers and Indigenous fishing communities have been organising globally to protect their rights.
Charlotte Spring, Jennifer Temmer, Kelly Skinner, Melaine Simba, Lloyd Chicot, Andrew Spring   +5 more
doaj   +1 more source

Global Symposium on Gender and Fisheries : Seventh Asian Fisheries Forum, 1-2 December 2004, Penang, Malaysia [PDF]

The 18 papers contained in this volume represent a substantive contribution to the literature on the topic of gender and fisheries. Drawing on work undertaken around the globe, the results described here confirm and extend earlier work and show that ...
Choo, Poh-Sze (ed.), Hall, S.J. (ed.), William, M.J. (ed.), WorldFish Cent. Penang (Malaysia)   +3 more
core  

Regional Workshop on Co-management in Small-Scale Fisheries: Lessons Learned and Best Practices 12-13 December 2012, Bangkok, Thailand [PDF]

, 2012
An FAO project, the Regional Fisheries Livelihoods Programme, which is funded by Spain, has worked with the Timorese authorities and coastal communities to build local capacity and put in place effective methods to gather a variety of important fisheries
Crispen Wilson, Don Griffiths, Enrique Alonso, Mario Pereira, Pedro Rodrigues, Steve Needham   +5 more
core  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Catch Shares in Action: Peruvian Anchoveta Northern-Central Stock Individual Vessel Quota Program [PDF]

, 2013
The Peruvian Anchoveta Northern-Central Stock Individual Vessel Quota Program is a catch share program that manages the largest volume fishery in the world.
Jeff Young, Kees Lankester
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

When co-management fails: a review of theory and lessons learned from reservoir fisheries in dry-zone of Sri Lanka [PDF]

Over recent decades co-management has become an increasingly popular form of governance reform in many developing countries. Viewed as a means of promoting sustainable and equitable management of natural resources, it has seen wide application in small ...
Murray, F.
core