Results 121 to 130 of about 752,939 (303)
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Small Signal Stability Analysis of Kurdistan Regional Power System
Abstract: This paper presents for the first time a mathematical model for evaluating the Planned Kurdistan RegionalPower System (KRPS) for its ability to maintain stability under small disturbances and fluctuations duringnormal operating conditions.
openaire +3 more sources
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Genetic Algorithms in Power System Small Signal Stability Analysis
Power system small signal stability analysis aims to explore different small signal stability conditions and controls, namely, 1) exploring the power system security domains and boundaries in the space of power system parameters of interest, including ...
Dong Yuri +3 more
core
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Power System Small Signal Stability Analysis Using Genetic Optimization Techniques
Power system small signal stability analysis aims to explore different small signal stability conditions and controls, namely, 1) exploring the power system security domains and boundaries in the space of power system parameters of interest, including ...
Yuri V. Makarov +2 more
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Small Signal Stability of an Unregulated Power System
Rotor angle stability is the ability of the interconnected synchronous machines of a power system to remain in synchronism. This stability problem is concerned with the behavior of one or more synchronous machine after they have been perturbed.
singhvi, vikas
core
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source

