Results 151 to 160 of about 6,718,160 (281)

Age‐Associated B Cells Contribute to Inflammation Via Antibody‐Independent Mechanisms in Takayasu Arteritis

Arthritis &Rheumatology, EarlyView.
Objective Although Takayasu arteritis (TAK) is not a prototypical autoantibody‐mediated disease, accumulating evidence suggests that B cells are involved. This study aimed to investigate the pathway of B cell activation and its contributions to TAK pathogenesis. Methods Histologic analysis of paravascular lymph nodes and affected arteries was conducted
Chenglong Fang, Xiaoxi Yang, Xiaochuan Sun, Shangyi Jin, Lihong Du, Jinwei Gao, Jing Li, Zhen Chen, Yuexin Chen, Mengtao Li, Xinping Tian   +10 more
wiley   +1 more source

Tenecteplase Averting Mechanical Thrombectomy in Emergent Large Vessel Occlusion

, 2019
Introduction:Tenecteplase has recently been studied as an alternative thrombolytic agent in acute stroke, with a possible superior effect in achieving reperfusion of large intracranial vessels.Case Report:A 90-year-old female patient was admitted to our ...
Tsivgoulis, G., Kargiotis, O., Magoufis, G., Stamboulis, E., Safouris, A., Liakakis, G., Psychogios, K.   +6 more
core   +1 more source

Accuracy of FAST-ED for Assessment Large Vessel Occlusion of Acute Ischemic Stroke in Emergency Department [PDF]

Chatchanan Pornpanit,1 Punnaporn Loymai,1 Nattaphol Uransilp,2 Winchana Srivilaithon1 1Department of Emergency Medicine, Faculty of Medicine, Thammasat University, Khlong Luang, Pathum Thani Province, Thailand; 2Division of Neurology, Department of ...
Uransilp N, Srivilaithon W, Pornpanit C, Loymai P   +3 more
core  

Student engagement in the anatomical sciences: What gets in the way?

Anatomical Sciences Education, EarlyView.
Abstract Active learning has become central to anatomical sciences education, yet its effectiveness largely depends on student engagement. Here we define the anatomical sciences as gross anatomy, surface anatomy, neuroanatomy, embryology, histology, and integrated radiology.
Kasidy K. Dobish, Kathryn B. Moore, Danielle M. Delucchi, Stephen L. Jenkins, Geoffrey T. Dorius, David A. Morton   +5 more
wiley   +1 more source

Serotype‐Tailored Midstream and Downstream Operations to Advance the Manufacturing of Adeno‐Associated Viral Vectors

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated viruses (AAVs) are the leading vectors for in vivo gene therapy, fueling a growing demand for scalable and robust biomanufacturing processes. Yet, the impact of cell lysis conditions on the performance of midstream and downstream unit operations across serotypes remains poorly characterized.
Arianna Minzoni, Shriarjun Shastry, Eduardo Barbieri, Morgan R. Hurst, Kelvin Idanwekhai, Yuxuan Wu, Katherine Ernst, Wai‐Keen Chung, Christopher Bombeck, Saad A. Khan, Sushmita Koley, Gabriella Kiss, Oliver Rammo, Alexander Tropsha, Cristiana Boi, Michael A. Daniele, Steven Cramer, Barry Byrne, Stephen Kaminsky, Angie Snell Bennett, Stefano Menegatti   +20 more
wiley   +1 more source

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

BMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang, Zhuomin Wang, Zhenhua Jin, Ahmed H. Ghonaim, Hengcheng Zhang, Xinyu You, Jinzhuo Ning, Jiaqing Cao, Yang Liu   +8 more
wiley   +1 more source

Acute Papillary Muscle Rupture due to Small Vessel Occlusion

Japanese Journal of Cardiovascular Surgery, 2012
Tsuda, Kazumasa, Koide, Masaaki, Kunii, Yoshifumi, Watanabe, Kazumasa, Miyairi, Satoshi   +4 more
openaire   +2 more sources

Engineering programmable peptide hydrogels for chronic refractory wounds: A mechanism‐driven framework

BMEMat, EarlyView.
To break the self‐perpetuating pathology of chronic wounds, we propose a mechanism‐driven engineering framework for peptide‐based hydrogels. This review elucidates a hierarchical strategy—from molecular design to intelligent, multi‐functional systems—that enables these programmable biomaterials to dynamically intervene in key pathological loops and ...
Xiaoyu Lv, Xinyi Chao, Jiamin Zhang, Jianfeng Liu   +3 more
wiley   +1 more source

Clinical Anatomy of the Left and Right Atrial Appendages in Humans: Comparative and Developmental Perspective

Clinical Anatomy, EarlyView.
ABSTRACT Human atrial chambers derive from distinct embryonic anlagens, the original embryonic atria gradually transforming into the so‐called auricles, or atrial appendages. This study quantifies macroscopic variations in pectinate muscle architecture in human atrial appendages and evaluates their visualization using clinical imaging modalities.
Markéta Lexová, Caroline Neradilová, Jan Kovanda, Jan Burkert, Jiří Beneš Jr., Martin Bartos, Theodor Adla, Vojtech Melenovsky, Alena Kvasilova, Ondrej Fabian, Ondrej Naňka, David Sedmera   +11 more
wiley   +1 more source

Five‐Year Clinical Outcomes of Biodegradable Versus Durable Polymer Drug‐Eluting Stents: A Propensity Score‐Matched Analysis of 4394 Patients

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Biodegradable‐polymer (BP) drug‐eluting stents (DES) were developed to mitigate potential late adverse events related to persistent durable polymers in durable‐polymer (DP) DES; however, contemporary long‐term real‐world comparative data remain limited. Aims We aimed to compare the 5‐year clinical outcomes of contemporary BP‐DES and
Yangyoun Lee, Hong‐Seok Lim, Kyoung‐Woo Seo, Hyoung‐Mo Yang, So‐Yeon Choi, Seung‐Jea Tahk, Myeong‐Ho Yoon   +6 more
wiley   +1 more source