Results 51 to 60 of about 229,913 (306)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

The impact of new urbanization pilot policies on carbon emissions in China’s small and medium-sized cities

open access: yesEnvironmental Research Communications
To combat global warming, advancing the shift from extensive traditional urbanization to intelligent, green, and low-carbon new urbanization is essential for the high-quality and sustainable development of the Chinese economy.
Jinguo Xin   +3 more
doaj   +1 more source

Immigrants and Homeownership in Urban America: An Examination of Nativity, Socio-economic Status and Place [PDF]

open access: yes, 2004
A unique pilot project conducted in America's small and medium-sized cities shows that broad-based community coalitions can proactively integrate the newcomers who are increasingly transforming Main St., USA.
Brian K. Ray   +2 more
core  

Barriers to the Development of SME's in the Australian Construction Industry [PDF]

open access: yes, 2012
Small and medium sized companies (SMEs) operating in the construction industry in regionalareas of Australia often struggle to compete against city-based companies for constructionwork.
Love, Peter, Mills, Anthony, Smith, Jim
core   +4 more sources

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Effects of tourism upon the economy of small and medium-sized European cities: Cultural tourists and 'the others' [PDF]

open access: yes, 2008
The paper presents the results of the application of an Input-Output-based approach for the estimation of direct, indirect and induced effects of tourist spending on local economies, in a static partial equilibrium setting.
Bellini, Elena   +3 more
core   +1 more source

Why Small and Medium-Sized Cities Matters?

open access: yes
In a rapidly urbanizing and warming world, natural hazard resilience is a pressing challenge. This is particularly true in Small and Medium Sized Cities (SMSC) where significant urban growth is projected through the mid-century, where there may be limited capacity to increase resilience and less adaptive capacity to respond to cascading and complex ...
Chandana Mitra, Natasha Picone
openaire   +2 more sources

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai   +5 more
wiley   +1 more source

Renovation of small and medium-sized cities in South Moravia and Lower Austria [PDF]

open access: yes, 2013
Problémy velkoměst se postupně přesouvají i na malá města. Jednou z cest, jak dosáhnout trvalé udržitelnosti může být právě kompaktní město.Problems of cities are gradually moving to small towns.
Navrátil, Václav
core  

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