Results 61 to 70 of about 288,471 (288)

Small and medium-sized enterprises managers' development support

Acta Universitatis Bohemiae Meridionalis, 2012
The management quality, the quality of the products, service and prosperities of the firms is among others dependent on the erudition and competition of the managers. Managers are obligated to create the atmosphere for improvement and looking for way to the enterprises competitiveness.
Darja Holátová, Dagmar Bednářová
openaire   +2 more sources

Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy

Advanced Science, EarlyView.
Autoantibodies against fibroblast growth factor receptor 3 (FGFR3) are identified as pathogenic drivers of pain in small fiber neuropathy. By binding to sensory neurons in dorsal root ganglia, FGFR3 autoantibodies activate MAPK signaling and induce hyperexcitability and mechanical hypersensitivity, establishing FGFR3 autoantibodies as a therapeutic ...
Lyuba Y. Salih, Nicolas L.A. Dumaire, Clémence Gieré, Erin Vest, Haya Alkhateeb, Christian P. Moritz, Yannick Tholance, Jean‐Philippe Camdessanché, Jean‐Christophe Antoine, Jérôme Honnorat, Jafar Kafaie, Liberty François‐Moutal, Aubin Moutal   +12 more
wiley   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

Multiple case-study analysis of quality management practices within UK Six Sigma and non-Six Sigma manufacturing small- and medium-sized enterprises [PDF]

, 2009
This paper examines multiple case-study analysis of quality management practices within UK Six Sigma and non-Six Sigma manufacturing small- and medium-sized ...
Boynton A., Eisenhardt K. M., Hamel G., J Antony, Lee C. Y., M Kumar, Morris P. J., Pyzdek T., Robson C., Rockart J., Yin R. Y.   +10 more
core   +1 more source

ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment

Advanced Science, EarlyView.
ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song, Siqi Chen, Lei Wang, Jessica Dang, Xu Cao, Stephanie Singh, Lu Yang, Jinhui Wang, Steven T. Rosen, Yingyu Wang, Chun‐Wei D. Chen, Cheng Zhang, Mingye Feng   +12 more
wiley   +1 more source

Knowledge Management in Small and Medium-Sized Enterprises

EUROPEAN RESEARCH STUDIES JOURNAL, 2020
Purpose: The main purpose of the research presented in the article was to diagnose the „knowledge management” process in small and medium-sized enterprises in the Lower Silesia Province. In order to achieve this goal, the first part of the article explains the meaning of the term „knowledge management" in the scientific literature on management, and ...
openaire   +3 more sources

Natural Negative Feedback Loops Confer Indica‐Japonica Differentiation for Grain Size Homeostasis in Rice

Advanced Science, EarlyView.
This study reveals the genetic and molecular mechanisms controlling grain size homeostasis through fine‐tuning OsGRX8 self‐expression by two natural negative feedback loops functioning in redox‐dependent or ‐independent manners and identifies two self‐regulatory haplotypes (SRHs) for the subspecies differentiation in rice.
Xingxing Li, Meng‐en Wu, Ziqi Qiao, Junkui Huang, Juncheng Zhang, Yang Ding, Junqing Zhu, Jingyue Xu, Yuxin Huang, Wei Li, Xiaomin Su, Yue Ding, Jianwei Zhang, Yibo Li   +13 more
wiley   +1 more source

SME Innovation in the Malaysian Manufacturing Sector [PDF]

This paper examines the determinants of innovation amongst small and medium enterprises in the Malaysian manufacturing sector using firm-level data. For small-sized firms, younger firms are more likely to innovate compared to older firms.
Cassey Lee, Lee Chew-Gin
core  

Transparent Transfer‐Free Ultrasmall Multilayer Graphene Microelectrodes Enable High Quality Recordings in Brain Slices

Advanced Science, EarlyView.
A transfer‐free fabrication method enables multilayer graphene microelectrodes as small as 10 µm, eliminating reliability issues of manual graphene transfer. These electrodes record neural activity in brain slices with exceptional signal‐to‐noise ratios (up to 25–40 dB) while maintaining optical transparency for multimodal applications.
Nerea de Alvarez de Eulate, Christos Pavlou, Gonzalo León González, María Camarena Pérez, Lukas Holzapfel, Zhenyu Gao, Sten Vollebregt, Vasiliki Giagka   +7 more
wiley   +1 more source

The Possibility of China’s Industrial Park Management Committee to Promote Interenterprise Cooperative Innovation in the Park: A Trilateral Evolutionary Game Perspective

Complexity, 2020
Under China’s distinct policy-driven agglomeration approach, the Chinese industrial park displays a low degree of industrial relevance and weak cooperation among enterprises in the park.
Zhuopin Guo, Jie Zhen, Yiying Qu, Hao Ren   +3 more
doaj   +1 more source