Results 61 to 70 of about 812,008 (296)

Implementing total productive maintenance in a manufacturing small or medium-sized enterprise

open access: yesJournal of Industrial Engineering and Management, 2021
Purpose: This paper develops a ‘light’ total productive maintenance (TPM) model suitable for small and medium-sized enterprises (SMEs). By design, the system is rudimentary, using a relatively small sum of capital investment and resources.
Zhang Tian Xiang, Chin Jeng Feng
doaj   +1 more source

Early independent production entrepreneurs in UK television: agents of a neo-liberal intervention [PDF]

open access: yes, 2017
This essay focuses on the operation of the UK independent television production sector in the context of the entrepreneurial aspirations of company owners in the 1990s.
Paterson, Richard
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

INCUBATORS AS A DEVELOPMENT MODEL FOR SMALL AND MEDIUM-SIZED COMPANIES

open access: yesEkonomika Poljoprivrede (1979), 2006
There is no doubt in the world today whether or not to support the founding and development of small and medium-sized companies. They have become an objective reality in all modern economies of the world.
Ljiljana Drinić, Nebojša Novković
doaj  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

The impact of emerging technologies and digitalization challenges on the expansion of international trade of small and medium-sized enterprises, considering the moderating role of industry type [PDF]

open access: yesرویکرد‌های نوین در مدیریت و بازاریابی
The aim of the study is to investigate the impact of technological tools, technological limitations and digitalization of trade on the development of international trade of small and medium-sized enterprises, moderating the type of industry (type of ...
Amir reza saati moghddam   +1 more
doaj   +1 more source

Penilaian Kandungan Komponen Teknologi Humanware Pada IKM (Studi Kasus: IKM Mebel Propinsi DI. YOGYAKARTA) [PDF]

open access: yes, 2012
One of methods performance improving in Small and Medium Industries is by improve technology capability. One of technology components is humanware, where human resource capability in a organization is determinant of organization's succesfull in facing ...
Umah, S. R. (Siti)
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Clusters as a vehicle for regional development - The case of Lublin Region [PDF]

open access: yes, 2011
Clusters are a specific form of spatial organization of various sectors of industry and services regarded as the most mature form of organization of production in the post-industrial era.
Bojar, Ewa, Bojar, Matylda
core  

Home - About - Disclaimer - Privacy