Results 71 to 80 of about 812,008 (296)
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Crystalline phase, surface morphology and electrical properties of monovalent-doped Nd0.75Na0.25Mn1-yCoyO3 manganites [PDF]
, 2017 Perovskite-type manganites Nd0.75Na0.25Mn1-yCoyO3 (y = 0 – 0.05) have been investigated to clarify the influence of Co-doped on crystal phase and morphological study as well as electrical transport properties.
Ab Mannan, Nurhabibah Nabilah +3 more
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
A silent cry for leadership : organizing for leading (in) clusters [PDF]
, 2010 Leadership research so far has neglected clusters as a particular context for leadership, while research on networks and clusters has hardly studied leadership issues.
Adams +104 more
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
THE AFRICAN GEOSPATIAL SCIENCES INSTITUTE (AGSI): A NEW APPROACH TO GEOSPATIAL TRAINING IN NORTH AFRICA [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2012 The African Geospatial Sciences Institute (AGSI) is currently being established in Tunisia as a non-profit, non-governmental organization (NGO). Its objective is to accelerate the geospatial capacity development in North-Africa, providing the facilities
S. Oeldenberger, K. B. Khaled
doaj +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
An investigation into the effects of computer integrated manufacturing systems in the productivity of SMEs in Pakistan [PDF]
, 2006 The current dynamic and turbulent manufacturing environment has forced companies that compete globally to change their traditional methods of conducting business [Producer to consumer].
Irani, Z, Marri, H B, Shaikh, G
core
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Development of Rural Manufacturing SME Clusters in a Developing Country: The Indonesian Case [PDF]
Development of manufacturing small and medium enterprises (SMEs) is a key engine to promote development of rural economy in developing countries. A common industrial organization among manufacturing SMEs, especially in rural areas, in Indonesia as in ...
Tambunan, Tulus
core +1 more source