Results 111 to 120 of about 5,772,088 (305)

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan, Jordan Safran, Anna Loughman, Grace Lin, Shivanshi Vaid, Dana Allababidi, Peter M. Tessier, Louis T. Dang   +7 more
wiley   +1 more source

The G8: Global arms exporters: Failing to prevent irresponsible arms transfers [PDF]

, 2005
The international arms trade lacks effective control. Irresponsible arms transfers continue to fuel armed violence. They contribute to violations of human rights and international humanitarian law and they undermine development.

core   +1 more source

View from Lort Street, Small Arms Factory, Bathurst [picture].

, 1943
Part of the collection: Photographic record of Small Arms Factory Group N.S.W., development & alterations from Dec. '42 to Dec.

core  

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Folder 22: AIDS ARMS Network - Newspaper Clippings, Correspondences from lawyers, meetings minutes, correspondence to John Thomas, 1986-1987, 1989-1993

, 1986
A document outlining the creation of the AIDS ARMS ...
AIDS ARMS Network, Inc.
core  

Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph, Megan McCune, Riley Bove, Ahmed Abdelhak, Bruce A. C. Cree, Valerie J. Block   +5 more
wiley   +1 more source

Folder 22: AIDS ARMS Network - Newspaper Clippings, Correspondences from lawyers, meetings minutes, correspondence to John Thomas, 1986-1987, 1989-1993

, 1990
A receipt of a payment from the AIDS ARMS Network, Inc. (Prism Health North Texas) to the AIDS Resource Center (Resource Center Dallas)
AIDS ARMS Network, Inc.
core   +1 more source

Folder 22: AIDS ARMS Network - Newspaper Clippings, Correspondences from lawyers, meetings minutes, correspondence to John Thomas, 1986-1987, 1989-1993

, 1991
A copy of some notes on AIDS ARMS Network's financial ...
AIDS ARMS Network, Inc.
core  

Small Arms Survey 2013 : Everyday Dangers /

Title from publisher's bibliographic system (viewed on 25 Nov 2014)
Small Arms Survey, Geneva
core   +1 more source

Pain and Patient‐Reported Physical Function Did Not Differ Among Body Composition Profiles in Patients With Hip Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan, Boliang Wang, Fiona Dobson, Ben Kirk, Travis Haber, Kim L. Bennell, Shirley P. Yu, Kim Allison, Ricardo J. S. Costa, Gabrielle Knox, Michelle Hall   +10 more
wiley   +1 more source