Results 161 to 170 of about 3,082,206 (396)

Small cell carcinoma of the ovary

Definitions, 2020

semanticscholar   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Small Cell Carcinoma of the Bladder

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2015
Small Cell Carcinoma of the bladder accounts for less than 1% of all bladder tumors. Small Cell Carcinoma of the bladder has an aggressive behaviour and is usually metastatic at diagnosis. Due to its infrequent occurence, the literature on this entity is
Tufan Cicek, Esra Zeynep Coskunoglu, Berkan Duran, Egemen Ciftci   +3 more
doaj  

Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma–like and Non–Small Cell Carcinoma–like Subsets

Clinical Cancer Research, 2016
N. Rekhtman, M. Pietanza, M. Hellmann, J. Naidoo, Arshi Arora, H. Won, D. Halpenny, Hangjun Wang, S. Tian, A. Litvak, P. Paik, A. Drilon, N. Socci, J. Poirier, R. Shen, M. Berger, A. Moreira, W. Travis, C. Rudin, M. Ladanyi   +19 more
semanticscholar   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

A complete pathological response to preoperative chemotherapy in a male patient with primary neuroendocrine breast cancer: a case report

Journal of Medical Case Reports
Background Primary neuroendocrine carcinoma (small-cell carcinoma) of the breast is a rare tumor; most cases are reported in women. Small-cell carcinoma is a type of neuroendocrine tumor characterized by high-grade, poorly differentiated, and aggressive ...
Maher Saifo, Rahaf Hussein, Eva Awad, Mohamad Al Chikh Youssef, Mousa Alali   +4 more
doaj   +1 more source

SOX2 and Rb1 in esophageal small-cell carcinoma: their possible involvement in pathogenesis

Modern Pathology, 2017
H. Ishida, A. Kasajima, T. Kamei, Tsuyoshi Miura, Naomi Oka, S. Yazdani, Y. Ozawa, F. Fujishima, A. Sakurada, Yasuhiro Nakamura, Yoichi Tanaka, M. Kurosumi, Y. Ishikawa, Y. Okada, N. Ohuchi, H. Sasano   +15 more
semanticscholar   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source